Registration Dossier
Registration Dossier
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EC number: 218-817-8 | CAS number: 2243-62-1
Endpoint summary
Administrative data
Description of key information
Irritation / corrosion:
In a study according to OECD guideline 404 the test substance was tested in a semiocclusive application of 500 mg/kg bw. in rabbits.
The exposure time was 4 h and the observation period 14 d.
No reddening or swelling of the tested skin region was observed. DRAIZE grade: 0
The test substance was not irritating or corrosive to the skin.
The test substance was tested accordingly to OECD guideline 405, were 100 µl (ca. 60 mg) of test material was applied to one eye of 3 rabbits.
The exposure time was 24 h and the observation time 21 d.
No reddening, swelling or lacrimal flow was observed.
The test substance was not irritating to the eye (Pauluhn 1986).
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Additional information
Justification for classification or non-classification
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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