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EC number: 204-627-2 | CAS number: 123-43-3
Endpoint summary
Administrative data
Description of key information
Biodegradation in water:
The biodegradability of test chemical sulphoacetic acid ( CAS no. 123 -43 -3) is predicted using OECD QSAR tool box v. 3.3 using log Kow as primary descriptor. Sulfoacetic acid showed 82 % degradation in 28 days using microorganisms as inoculum and BOD as a parameter. Hence, it is concluded that the chemical sulphoacetic acid is readily biodegradable.
Biodegradation in water and sediments:
Estimation Programs Interface (EPI Suite, 2017) prediction model was run to predict the half-life in water and sediment for the test compound Sulfoacetic acid (CAS No: 123-43-3) .If released in to the environment, 33.5 % of the chemical will partition into water according to the Mackay fugacity model level III and the half-life period of Sulfoacetic acid (CAS No: 123-43-3) in water is estimated to be 8.66 days (208 hrs). The half-life (8.66 days estimated by EPI suite) indicates that the chemical is not persistent in water and the exposure risk to aquatic animals is moderate to low whereas the half-life period of test chemical Sulfoacetic acid (CAS No: 123-43-3) in sediment is estimated to be 77.91 days (1870 hrs) indicates that test chemical is not persistent in sediment.
Biodegradtion in soil:
The half-life period of Sulfoacetic acid (CAS No: 123-43-3) in soil was estimated using Level III Fugacity Model by EPI Suite version 4.1 estimation database (EPI suite, 2017). If released into the environment, 66.5% of the chemical will partition into soil according to the Mackay fugacity model level III. The half-life period of Sulfoacetic acid (CAS No: 123-43-3) in soil is estimated to be 17.33 days (416 hrs). Based on this half-life value of Sulfoacetic acid (CAS No: 123-43-3, it is concluded that the chemical Sulfoacetic acid (CAS No: 123-43-3) is not persistent in the soil environment and the exposure risk to soil dwelling animals is moderate to low.
Additional information
Biodegradation in water:
Predictated data for target chemical Sulphoacetic acid ( CAS no. 123 -43 -3) and supporting weight of evidence studies for its closest read across substance with log Kow as a primary descriptor were reviewed for biodegradation endpoint which are summarized as below.
The biodegradability of test chemical sulphoacetic acid ( CAS no. 123 -43 -3) is predicted using OECD QSAR tool box v. 3.3 using log Kow as primary descriptor. Sulfoacetic acid showed 82 % degradation in 28 days using microorganisms as inoculum and BOD as a parameter.
In another estimation study using Estimation Programs Interface Suite (EPI suite, 2017), biodegradation potential of the test compound Sulfoacetic acid (CAS No: 123-43-3) was predicted in the presence of mixed populations of environmental microorganisms. The biodegradability of the substance was calculated using seven different models such as Linear Model, Non-Linear Model, Ultimate Biodegradation Timeframe, Primary Biodegradation Timeframe, MITI Linear Model, MITI Non-Linear Model and Anaerobic Model (called as Biowin 1-7, respectively) of the BIOWIN v4.10 software. The results indicate that chemical Sulfoacetic acid (CAS No: 123-43-3) is expected to be readily biodegradable
In a supporting weight of evidence study from secondary source ( J check, 2017) for read across chemical Diethyl Oxalate (CAS no. 95-92-1), biodegradation experiment was performed for 28 days for evaluating the percentage biodegradability. Concentration of inoculum i.e, sludge used was 30 mg/l and initial test substance conc. used in the study was 100 mg/l. The percentage degradation of test substance was determined to be 80% degradation by BOD and 100% degradation by TOC removal and by HPLC parameter in 28 days. These values of percentages are more than 70, so read across chemical Diethyl oxalate is considered to be readily biodegradable .
In another supporting weight of evidence study from secondary source ( J check, 2017) for read across chemical 1, 4-Butanedicarboxylic acid (CAS no. 124-04-9), biodegradation experiment was performed for 14 days for evaluating the percentage biodegradability. Concentration of inoculum i.e, sludge used was 30 mg/l and initial test substance conc. used in the study was 100 mg/l. The percentage degradation of read across substance 1, 4-Butanedicarboxylic acid was determined to be 81% degradation by BOD, 98 % degradation by TOC removal and 100% degradation by HPLC parameter in 14 days. Thus, based on percentage degradation, 1, 4-Butanedicarboxylic acid – is considered to be readily biodegradable in water.
On the basis of above results for target chemical sulphoacetic acid ( from OECD QSAR tool box v.3.3 and EPI suite) and for its read across from secondary source, it can be concluded that the test sunstance is expected to be readily biodegradable in nature.
Biodegradation in water and sediments:
Estimation Programs Interface (EPI Suite, 2017) prediction model was run to predict the half-life in water and sediment for the test compound Sulfoacetic acid (CAS No: 123-43-3) .If released in to the environment, 33.5 % of the chemical will partition into water according to the Mackay fugacity model level III and the half-life period of Sulfoacetic acid (CAS No: 123-43-3) in water is estimated to be 8.66 days (208 hrs). The half-life (8.66 days estimated by EPI suite) indicates that the chemical is not persistent in water and the exposure risk to aquatic animals is moderate to low whereas the half-life period of test chemical Sulfoacetic acid (CAS No: 123-43-3) in sediment is estimated to be 77.91 days (1870 hrs) indicates that test chemical is not persistent in sediment.
Biodegradtion in soil:
The half-life period of Sulfoacetic acid (CAS No: 123-43-3) in soil was estimated using Level III Fugacity Model by EPI Suite version 4.1 estimation database (EPI suite, 2017). If released into the environment, 66.5% of the chemical will partition into soil according to the Mackay fugacity model level III. The half-life period of Sulfoacetic acid (CAS No: 123-43-3) in soil is estimated to be 17.33 days (416 hrs). Based on this half-life value of Sulfoacetic acid (CAS No: 123-43-3, it is concluded that the chemical Sulfoacetic acid (CAS No: 123-43-3) is not persistent in the soil environment and the exposure risk to soil dwelling animals is moderate to low.
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