Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 701-072-2 | CAS number: -
Partition coefficient
Administrative data
Link to relevant study record(s)
Description of key information
Waived: Measurement of octanol-water partition cannot be performed, due to reactive and UVCB nature of the substance
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 4.51
- at the temperature of:
- 20 °C
Additional information
The test substance is covered by the category approach of methylenediphenyl diisocyanates (MDI). Hence, data of the category substances can be used to cover this endpoint. The n-octanol/water partitioning coefficient was determined with MDI mixed isomers (Yakabe et al., 2000). The test was done according to OECD 117 with the HPLC method. The fact that only one sharp peak was observed in the chromatogram indicates that the two isomers (4,4'-MDI and 2,4'-MDI) present in the test material have very similar log Pow values. As the addition of DPG and/or TPG to MDI would result in increased values of log Pow, and because the MDI/DPG/TPG substance can be expected to contain some amount of unreacted 4,4'-MDI, the log Pow is reported as "log Pow > 4.5".
However, given the reactivity of MDI and MDI/DPG/TPG prepolymer in the aquatic environment and its transient existence in water, the log Pow has little direct relevance to the calculation of its environmental fate and ecotoxicity.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
