Guanidinium thiocyanate

pH

Administrative data

Endpoint:

pH

Type of information:

experimental study

Adequacy of study:

key study

Study period:

04/2021

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

comparable to guideline study with acceptable restrictions

Cross-reference

Reason / purpose for cross-reference:

reference to same study

Reference

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2021-03-01 - 2021-04-30

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 105 (Water Solubility)

GLP compliance:

no

Type of method:

flask method

Specific details on test material used for the study:

Lot 2103311210

Key result

Water solubility:

ca. 1 562 g/L

Conc. based on:

test mat.

Incubation duration:

> 24 - <= 120 h

Temp.:

20 °C

pH:

ca. 6.2

Conclusions:

The mean watersolubility of Guanidinium thiocyanate is 1562 g/L at 20 +/- 0.5 °C.
The pH of the satureted solution is 6.2.

Executive summary:

The solubility of Guanidinium Thiocyanate was determined in water at a temperature of 20 ± 0.5 °C according to OECD guideline 105 (Shake Flask) with restrictions.
The results are presented in the following table:

Solubility of guanidinium thiocyanate in water at 20 ± 0.5 °C

Determined pH	6.2
Mean solubility [g/L]	1562

The repeated samplings indicate the required reproducibility (relative standard deviation below 15%).

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2021

Report date:

2021

Materials and methods

Test guideline

Guideline:

other: OECD 105

GLP compliance:

no

Test material

Test material information

Constituent 1

Reference substance name:

Guanidinium thiocyanate

EC Number:

209-812-1

EC Name:

Guanidinium thiocyanate

Cas Number:

593-84-0

Molecular formula:

CH5N3.CHNS

IUPAC Name:

amino(imino)methanaminium thiocyanate

impurity 1

Reference substance name:

unknown

IUPAC Name:

unknown

Test material form:

solid: bulk

Specific details on test material used for the study:

Lot2103311210

Results and discussion

pH value

Key result

pH value:

6.2

Temp.:

20 °C

Concentration:

1 562 g/L

Applicant's summary and conclusion

Conclusions:

The pH of a satureted solution of GTC is 6.2

Executive summary:

In a watersolubility study according to OECD 105 with GTC the pH of the saturated solution was determined.