Registration Dossier
Registration Dossier
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EC number: 230-086-7 | CAS number: 6940-53-0
Partition coefficient
Administrative data
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- May 2008
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Well documented, recent guideline study.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 008
- Report date:
- 2008
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
- Deviations:
- not specified
- GLP compliance:
- not specified
- Type of method:
- shake-flask method to: flask method
- Partition coefficient type:
- octanol-water
Test material
- Reference substance name:
- 1-chloro-2,5-dimethoxy-4-nitrobenzene
- EC Number:
- 230-086-7
- EC Name:
- 1-chloro-2,5-dimethoxy-4-nitrobenzene
- Cas Number:
- 6940-53-0
- Molecular formula:
- C8H8ClNO4
- IUPAC Name:
- 1-chloro-2,5-dimethoxy-4-nitrobenzene
Constituent 1
Study design
- Analytical method:
- photometric method
Results and discussion
Partition coefficient
- Type:
- log Pow
- Partition coefficient:
- 2.03
- Temp.:
- 23 °C
- pH:
- >= 6 - <= 8
Any other information on results incl. tables
Results in detail:
determ. no. |
stock solution
[ml] |
water
[ml] |
test substance conc. in n-octanol phase [mg/l] |
test substance conc. in water phase [mg/l] |
ratio water : n-octanol |
log Pow |
A1 |
10 |
20 |
635.2 |
4.2 |
2 : 1 |
2.18 |
A2 |
10 |
20 |
630.5 |
4.5 |
2 : 1 |
2.15 |
B1 |
20 |
20 |
626.5 |
5.8 |
1 : 1 |
2.03 |
B2 |
20 |
20 |
633.7 |
5.6 |
1 : 1 |
2.06 |
C1 |
40 |
20 |
627.9 |
8.4 |
1 : 2 |
1.88 |
C2 |
40 |
20 |
625.8 |
8.3 |
1 : 2 |
1.88 |
mean |
-- |
-- |
-- |
-- |
-- |
2.03 |
Recovery rate of test substance:
determ. no. |
test substance in stock solution [mg] |
test substance in n-octanol phase [mg] |
test substance in water phase [mg] |
sum
[mg] |
recovery rate
[%] |
A1 |
6.43 |
6.35 |
0.08 |
6.44 |
100 |
A2 |
6.43 |
6.30 |
0.09 |
6.39 |
99 |
B1 |
12.86 |
12.53 |
0.12 |
12.65 |
98 |
B2 |
12.896 |
12.67 |
0.11 |
12.78 |
99 |
C1 |
25.72 |
25.12 |
0.17 |
25.29 |
98 |
C2 |
25.72 |
25.03 |
0.17 |
25.20 |
98 |
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
