Registration Dossier
Registration Dossier
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EC number: 261-867-0 | CAS number: 59703-00-3
Short-term toxicity to fish
Administrative data
- Endpoint:
- short-term toxicity to fish
- Type of information:
- (Q)SAR
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with limited documentation / justification
- Justification for type of information:
- 1. SOFTWARE
EPI v4.11
2. MODEL (incl. version number)
ECOSAR v1.11
3. SMILES OR OTHER IDENTIFIERS USED AS INPUT FOR THE MODEL
CCN1CCN(C(=O)(CL))C(=O)C1(=O)
4. SCIENTIFIC VALIDITY OF THE (Q)SAR MODEL
- Defined endpoint: Short time fish
Data source
Reference
- Reference Type:
- other: QSAR model
- Title:
- EPI Suite v 4.1/ECOSARv1.11
- Author:
- US EPA
- Year:
- 2 011
- Bibliographic source:
- http://epa.gov/oppt/exposure/pubs/episuite.htm
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: REACH Guidance on QSARs R.6
- GLP compliance:
- no
Test material
- Reference substance name:
- 4-ethyl-2,3-dioxopiperazine-1-carbonyl chloride
- EC Number:
- 261-867-0
- EC Name:
- 4-ethyl-2,3-dioxopiperazine-1-carbonyl chloride
- Cas Number:
- 59703-00-3
- Molecular formula:
- C7H9ClN2O3
- IUPAC Name:
- 4-ethyl-2,3-dioxopiperazine-1-carbonyl chloride
Constituent 1
Results and discussion
Effect concentrations
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- 615.826 mg/L
- Nominal / measured:
- estimated
- Conc. based on:
- not specified
- Basis for effect:
- not specified
- Remarks on result:
- not determinable because of methodological limitations
Applicant's summary and conclusion
- Conclusions:
- LC50 (96h) 615.826 mg/l is predicted
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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