Registration Dossier

Administrative data

Description of key information

No studies have been performed regarding the skin and eye irritation properties of the title substance. Based on the assessment of animal studies with two structural similar substances reagrding skin and eye irritation (LPT, 2013), it is concluded that the title substance is not irritating to skin or eyes.

Key value for chemical safety assessment

Skin irritation / corrosion

Endpoint conclusion
Endpoint conclusion:
no study available

Eye irritation

Endpoint conclusion
Endpoint conclusion:
no study available

Respiratory irritation

Endpoint conclusion
Endpoint conclusion:
no study available

Additional information

No animal studies have been performed regarding the skin and eye irritation properties of the title substance. Due to the fact that studies are available for two structural similar substances, further testing was omitted and a read across approach according to REACH Annex XI, 1.5. was chosen. A detailed text "Justification for a read-across approach according to Regulation (EC) No 1907/2006, Annex XI, 1.5 using the reporting format for analogues according to the Guidance on information requirements and chemical safety assessment, Chapter R.6.2.6. for xxx" is attached to this endpoint summary.

Based on this evaluation and the available data of these two structural similar substances it can be concluded that the title substance is not irritating to skin and eyes.

However, since no definite study is available for skin and eye irritation a data waiver is claimed.


Justification for selection of skin irritation / corrosion endpoint:
Data regarding skin irritation are not availbale. A data waiver is claimed.

Justification for selection of eye irritation endpoint:
Data regarding eye irritation are not available. A data waiver is claimed.

Justification for classification or non-classification

According to criteria of EC Directive 67/548/EEC and EC Regulation

1272/2008 the title substance is not irritating to skin and eyes.