Registration Dossier

Diss Factsheets

Environmental fate & pathways

Biodegradation in water: screening tests

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

Phthalonitrile is not readily biodegradable (according to OECD criteria) but moderately biodegradable and it can be easily eliminated from water. After adaption, it is biodegradable.

Key value for chemical safety assessment

Additional information

A study according to OECD TG 301E (BASF 1989, 02/0662/20/1) conducted with non-adapted domestic activated sludge resulted in a biodegradation of ca. 56-59% after 30 days related to the DOC removal. After 4 days of the test plateau is reached which is kept until the end of the test. An unknown metabolite might suppress further biodegradation.


The same test according to OECD TG 301 E was conducted in parallel with adapted inoculum taken from a BASF laboratory STP showing higher rates of biodegradation up to 95% after 21 days (BASF 1989, 02/0662/20/88). This result indicates that the suppressing metabolite can be biodegraded after adaption.