Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 304-990-8 | CAS number: 94313-91-4
Endpoint summary
Administrative data
Link to relevant study record(s)
Description of key information
TOXICOKINETIC BEHAVIOUR
Physico-chemical properties:
Trimethyl-3-[(1-oxo-10-undecenyl)amino]propylammonium methyl sulphateis an off white solid at ambient temperature of 20 degC and pressure of 101.3 kPa and the molecular weight is 394.57 g/mol.
The calculated LogP (octanol-water) of the substance is -0.73 at 20 degC and the substance is readily soluble in water. The vapour pressure was calculated to be 0.189 Pa at 20 degC.
Absorption:
There are no directly measured ADME data by any route for the substance.
Oral: In the key study for acute oral toxicity (Evonik, 1983), there are no reported systemic effects and no indication of the extent of absorption when the substance was dosed by gavage in water. The high degree of water solubility and molecular weight <500 g/mol would indicate that this substance would absorb well through the gut and into the systemic circulation.
Inhalation: The substance is not volatile and is not expected to be inhaled to any significant extent.
Dermal: The substance is classified as a category 2 skin irritant. Damage to the skin barrier will increase the potential for this substance to absorb into the systemic circulation. It is not a skin sensitiser in guinea pigs. Given the high solubility in water and the relatively low logP, it is expected that skin absorption will be relatively low.
Distribution:
There are no specific data on differential distribution to organs.
Metabolism:
There is also no information on metabolism of this substance.
There is no evidence from in vitro genotoxicity studies to suggest that metabolism plays a role in the genotoxic properties of this substance. The substance is non genotoxic in the absence and presence of metabolic activation.
Excretion:
No data are available to determine the pathways or extent of excretion.
Key value for chemical safety assessment
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
