Registration Dossier
Registration Dossier
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EC number: 266-405-1 | CAS number: 66557-45-7
Endpoint summary
Administrative data
Description of key information
Based on the data presented, the test substance Disperse Violet 93:1 (Br) seems to react as a skin sensitiser at concentration of ≥ 25% if the animals were pre-treated with an adjuvant. Without adjuvant, concentrations of up to 12.5% did not cause skin sensitising effects. The source substance Disperse Violet 93.1 Cl is therefore considered positive in skin sensitising properties and classified as Skin Sens. 1.
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (sensitising)
Respiratory sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no study available
Justification for classification or non-classification
Based on the data presented, the test substance Disperse Violet 93:1 (Br) seems to react as a skin sensitiser at concentration of ≥ 25% if the animals were pre-treated with an adjuvant. Without adjuvant, concentrations of up to 12.5% did not cause skin sensitising effects.
Although the outcome of the various skin sensitisation study does not give a clear picture, it was concluded to classify the test substance as skin sensitiser, as Disperse Blue 165:1, for which Disperse Violet 93:1 is the precursor in the synthesis process, was positive in the Local Lymph Node assay.
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