Registration Dossier
Registration Dossier
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EC number: 289-969-0 | CAS number: 90046-02-9 Extractives and their physically modified derivatives such as tinctures, concretes, absolutes, essential oils, oleoresins, terpenes, terpene-free fractions, distillates, residues, etc., obtained from Juniperus oxycedrus, Cupressaceae.
Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- secondary literature
Data source
Reference
- Reference Type:
- publication
- Title:
- Fragrance raw materials monographs. CADE OIL RECTIFIED (JUNIPER TAR)
- Author:
- Opdyke
- Year:
- 1 975
- Bibliographic source:
- Food and Cosmetics Toxicology, 13(6), 733–734.
Materials and methods
Test guideline
- Qualifier:
- no guideline available
- GLP compliance:
- no
- Remarks:
- pre-GLP
Test material
- Reference substance name:
- Juniper, Juniperus oxycedrus, ext.
- EC Number:
- 289-969-0
- EC Name:
- Juniper, Juniperus oxycedrus, ext.
- Cas Number:
- 90046-02-9
- IUPAC Name:
- Empyreumatic oil obtained from Juniperus oxycedrus (Cupressaceae) wood by dry distillation
- Test material form:
- not specified
Constituent 1
Test animals
- Species:
- rabbit
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- >= 5 000 mg/kg bw
- Based on:
- test mat.
Applicant's summary and conclusion
- Conclusions:
- The acute dermal LD50 of juniper tar to rats was reported to exceed 5000 mg/kg.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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