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Diss Factsheets
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EC number: 226-070-4 | CAS number: 5261-31-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
![](https://chesar.echa.europa.eu/o/diss-blank-theme/images/factsheets/A-REACH/factsheet/print_environmental-fate-and-pathways.png)
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: inherent biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- From September 10, 1997 to October 08, 1997
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study without detailed documentation
- Remarks:
- abstract
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 302 C (Inherent Biodegradability: Modified MITI Test (II))
- GLP compliance:
- no
- Inoculum or test system:
- other: sludge
- Remarks:
- 100 mg/L suspended solids
- Details on inoculum:
- Waste water plan: ARA - PRO RHENO Basel communal
- Duration of test (contact time):
- 28 d
- Initial conc.:
- 30 mg/L
- Based on:
- ThOD
- Remarks:
- ThOD: 1.21 mg O2/mg
- Parameter followed for biodegradation estimation:
- other: biochemical oxygen demand
- Details on study design:
- An automated closed-system oxygen consumption measuring apparatus (BOD-meter) was used in this experiment.
- Reference substance:
- other: not specified
- Key result
- Parameter:
- other: mean biodegradation (%)
- Value:
- 6
- Sampling time:
- 28 d
- Key result
- Parameter:
- BOD5
- Value:
- 0 mg O2/g test mat.
- Remarks on result:
- other: after 5 d
- Results with reference substance:
- Biodegradation of the reference substance after 14 d: 80%
- Validity criteria fulfilled:
- not specified
- Interpretation of results:
- not inherently biodegradable
- Conclusions:
- Under the study conditions, the test substance biodegradation was equivalent to 6% after 28 d. The test substance was therefore not considered to be inherently biodegradable.
- Executive summary:
A study was conducted to determine the inherent biodegradability of the test substance according to OECD Guideline 302 C. Sludge (100 mg/L suspended solids) from a predominantly domestic wastewater treatment plant was exposed for 28 d to the test substance at a concentration of 30 mg/L. The theoretical oxygen demand (ThOD) was 1.21 mg 02/mg. The test setup also included a standard reference substance. The biodegradation of the reference substance after 14 d was determined to be 80%. Under the study conditions, the test substance biodegradation was equivalent to 6% after 28 d. The test substance was therefore not considered to be inherently biodegradable (Dietschy, 1997).
- Endpoint:
- biodegradation in water: inherent biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- From July 22, 1992 to August 08, 1992
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study without detailed documentation
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 302 B (Inherent biodegradability: Zahn-Wellens/EMPA Test)
- GLP compliance:
- no
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, industrial (adaptation not specified)
- Remarks:
- 1020 mg/L suspended solids
- Details on inoculum:
- From ARA Rhein Industrie
- Duration of test (contact time):
- 28 d
- Initial conc.:
- 398 mg/L
- Based on:
- DOC
- Parameter followed for biodegradation estimation:
- TOC removal
- Remarks:
- %
- Reference substance:
- diethylene glycol
- Remarks:
- 153.6 mg/L
- Key result
- Parameter:
- % degradation (TOC removal)
- Value:
- 33.1
- Sampling time:
- 28 d
- Details on results:
- DOC (%): 37.7
- Results with reference substance:
- diethylene glycol (14 d biodegradation): 100%
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- inherently biodegradable
- Conclusions:
- Under the study conditions, the test substance biodegradation was equivalent to be 33.1%. The test substance was therefore not considered to be inherent biodegradable.
- Executive summary:
A study was conducted to determine the inherent biodegradability of the test substance according to OECD Guideline 302 B. Sludge (1020 mg/L suspended solids) from a predominantly domestic wastewater treatment plant was exposed for 28 d to the test substance at a concentration of 398 mg/L (corresponding to 120.6 mg a.i./L). The test setup also included a reference substance, diethylene glycol at 153.6 mg/L. Degradation of the test substance in terms of % TOC was monitored for 28 d. The biodegradation of the reference substance after 14 d was determined to be 100%. Under the study conditions, the test substance biodegradation was equivalent to 33.1%. The test substance was therefore not considered to be inherent biodegradable (Dietschy, 1992).
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study without detailed documentation
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 D (Ready Biodegradability: Closed Bottle Test)
- GLP compliance:
- not specified
- Inoculum or test system:
- not specified
- Duration of test (contact time):
- 28 d
- Initial conc.:
- 6 mg/L
- Reference substance:
- aniline
- Key result
- Parameter:
- % degradation (O2 consumption)
- Value:
- 5
- Sampling time:
- 28 d
- Remarks on result:
- other: not readily biodegradable
- Results with reference substance:
- Aniline (28 d, ready biodegradability %): 78
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- not readily biodegradable
- Conclusions:
- Under the study conditions, the test substance biodegradation was equivalent to 5% after 28 d. The test substance was therefore not considered to be readily biodegradable.
- Executive summary:
A study was conducted to determine the ready biodegradability of the test substance according to OECD Guideline 301 D. The inoculum (6 mg/L) was exposed for 28 d to the test substance. The oxygen demand was monitored for 28 d. The test setup also included the reference substance aniline. The biodegradation of the reference substance after 14 d was determined to be 75%. Under the study conditions, the test substance biodegradation was equivalent to 5% after 28 d. The test substance was therefore not considered to be readily biodegradable (Mueller, 1993).
Referenceopen allclose all
Description of key information
Key value for chemical safety assessment
- Biodegradation in water:
- under test conditions no biodegradation observed
Additional information
A study was conducted to determine the ready biodegradability of the test substance according to OECD Guideline 301 D. The inoculum (6 mg/L) was exposed for 28 d to the test substance. The oxygen demand was monitored for 28 d. The test setup also included the reference substance aniline. The biodegradation of the reference substance after 14 d was determined to be 75%. Under the study conditions, the test substance biodegradation was equivalent to 5% after 28 d. The test substance was therefore not considered to be readily biodegradable (Mueller, 1993).
A study was conducted to determine the inherent biodegradability of the test substance according to OECD Guideline 302 C. Sludge (100 mg/L suspended solids) from a predominantly domestic wastewater treatment plant was exposed for 28 d to the test substance at a concentration of 30 mg/L. The theoretical oxygen demand (ThOD) was 1.21 mg 02/mg. The test setup also included a standard reference substance. The biodegradation of the reference substance after 14 d was determined to be 80%. Under the study conditions, the test substance biodegradation was equivalent to 6% after 28 d. The test substance was therefore not considered to be inherently biodegradable (Dietschy, 1997).
A study was conducted to determine the inherent biodegradability of the test substance according to OECD Guideline 302 B. Sludge (1020 mg/L suspended solids) from a predominantly domestic wastewater treatment plant was exposed for 28 d to the test substance at a concentration of 398 mg/L (corresponding to 120.6 mg a.i./L). The test setup also included a reference substance, diethylene glycol at 153.6 mg/L. Degradation of the test substance in terms of % TOC was monitored for 28 d. The biodegradation of the reference substance after 14 d was determined to be 100%. Under the study conditions, the test substance biodegradation was equivalent to 33.1%. The test substance was therefore not considered to be inherent biodegradable (Dietschy, 1992).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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