Registration Dossier

Administrative data

Endpoint:
in vivo mammalian somatic cell study: cytogenicity / erythrocyte micronucleus
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data

Data source

Reference
Reference Type:
review article or handbook
Title:
An update to the toxicological profile for water-soluble and sparingly soluble tungsten substances
Author:
Lemus R. and Venezia C.
Year:
2015
Bibliographic source:
Critical Reviews in Toxicology 45 (5), pp 388-311

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)

Test material

Constituent 1
Chemical structure
Reference substance name:
Disodium wolframate
EC Number:
236-743-4
EC Name:
Disodium wolframate
Cas Number:
13472-45-2
Molecular formula:
Na.1/2O4W
IUPAC Name:
disodium dioxido(dioxo)tungsten

Results and discussion

Test results
Genotoxicity:
negative

Applicant's summary and conclusion