Calcination products of titanium dioxide, tin monoxide, zinc oxide and dihydrogen wolframate

Genetic toxicity: in vivo

Administrative data

Endpoint:

in vivo mammalian somatic cell study: cytogenicity / erythrocyte micronucleus

Type of information:

experimental study

Adequacy of study:

supporting study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

data from handbook or collection of data

Data source

Reference

Reference Type:

review article or handbook

Title:

An update to the toxicological profile for water-soluble and sparingly soluble tungsten substances

Author:

Lemus R. and Venezia C.

Year:

2015

Bibliographic source:

Critical Reviews in Toxicology 45 (5), pp 388-311

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

OECD Guideline 474 (Mammalian Erythrocyte Micronucleus Test)

Test material

Test material information

Constituent 1

Reference substance name:

Disodium wolframate

EC Number:

236-743-4

EC Name:

Disodium wolframate

Cas Number:

13472-45-2

Molecular formula:

Na.1/2O4W

IUPAC Name:

disodium dioxido(dioxo)tungsten

Results and discussion

Test results

Genotoxicity:

negative