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Environmental fate & pathways

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Description of key information

Biodegradation:

Biodegradation in water:

Biodegradability of test chemical sodium 2-[(1-oxododecyl)amino]ethanesulphonate (CAS no. 70609-66-4) was predicted using OECD QSAR tool box.v.3.3 using log Kow as primary descriptor. The test chemical sodium 2-[(1-oxododecyl)amino]ethanesulphonate showed 84.2 % biodegradability in 28 days by considering BOD as parameter and microorganisms as inoculum. Therefore it is concluded that the test chemical sodium 2-[(1-oxododecyl)amino]ethanesulphonate is readily biodegradable.

Biodegradation in water and sediments:

Estimation Programs Interface (EPI Suite, 2017) prediction model was run to predict the half-life in water and sediment for the test compound sodium 2-[(1-oxododecyl)amino]ethanesulphonate (CAS No. 70609-66-4). If released in to the environment, 23 % of the chemical will partition into water according to the Mackay fugacity model level III and the half-life period of test chemical sodium 2-[(1-oxododecyl)amino]ethanesulphonate in water is estimated to be 15 days (360 hrs). The half-life (15 days estimated by EPI suite) indicates that the chemical is not persistent in water and the exposure risk to aquatic animals is moderate to low whereas the half-life period of test chemical sodium 2-[(1-oxododecyl)amino]ethanesulphonate in sediment is estimated to be 135 days (3240  hrs).  However as the percent release of test chemical sodium 2-[(1-oxododecyl)amino]ethanesulphonate into sediment is less than 1 % (i.e., reported as 0.215% ) indicates that test chemical sodium 2-[(1-oxododecyl)amino]ethanesulphonate is not persistant in sediments.

Biodegradation in soil:

The half-life period of test chemical sodium 2-[(1-oxododecyl)amino]ethanesulphonate (CAS No. 70609-66-4) in soil was estimated using Level III Fugacity Model by EPI Suite version 4.1 estimation database (EPI suite, 2017). If released into the environment, 76.2 % of the chemical will partition into soil according to the Mackay fugacity model level III. The half-life period of test chemicalsodium 2-[(1-oxododecyl)amino]ethanesulphonatein soil is estimated to be 30 days (720 hrs). Based on this half-life value of test chemicalsodium 2-[(1-oxododecyl)amino]ethanesulphonate, it is concluded that the chemical is not persistent in the soil environment and the exposure risk to soil dwelling animals is low.

Bioaccumulation:

Bioaccumulation: aquatic / sediment:

Using BCFBAF Program (v3.00) model of EPI suite 2017 the estimated bio concentration factor (BCF) for sodium 2-[(1-oxododecyl)amino]ethanesulphonate (CAS No. 70609-66-4) is 70.79 L/kg wet-wt at 25 deg. c which does not exceed the bioconcentration threshold of 2000. Therefore it is concluded that test chemical sodium 2-[(1-oxododecyl)amino]ethanesulphonate is non bioaccumulative in food chain.

Transport and Distribution:

Adsorption / desorption:

The Soil Adsorption Coefficient i.e. Koc value of test chemical sodium 2-[(1-oxododecyl)amino]ethanesulphonate (CAS No. 70609-66-4) was estimated using EPI suite KOCWIN Program (v2.00) as 194.1 L/kg (log Koc= 2.2880) by means of MCI method at 25 deg. C. This log Koc value indicates that test chemical sodium 2-[(1-oxododecyl)amino]ethanesulphonate has low sorption to soil and therefore have moderate migration potential to ground water.

Additional information

Biodegradation:

Biodegradation in water:

Predicted data for the target compound sodium 2-[(1-oxododecyl)amino]ethanesulphonate (CAS no. 70609-66-4) and supporting weight of evidence studies for its read across substance were reviewed for the biodegradation end point which are summarized as below:

Biodegradability of test chemical sodium 2-[(1-oxododecyl)amino]ethanesulphonate (CAS no. 70609-66-4) was predicted using OECD QSAR tool box.v.3.3 using log Kow as primary descriptor. The test chemical sodium 2-[(1-oxododecyl)amino]ethanesulphonate showed 84.2 % biodegradability in 28 days by considering BOD as parameter and microorganisms as inoculum. Therefore it is concluded that the test chemical sodium 2-[(1-oxododecyl)amino]ethanesulphonate is readily biodegradable.

Another prediction done by using Estimation Programs Interface Suite (EPI suite, 2017) to estimate the biodegradation potential of the test compound sodium 2-[(1-oxododecyl)amino]ethanesulphonate (CAS no. 70609-66-4) in the presence of mixed populations of environmental microorganisms. The biodegradability of the substance was calculated using seven different models such as Linear Model, Non-Linear Model, Ultimate Biodegradation Timeframe, Primary Biodegradation Timeframe, MITI Linear Model, MITI Non-Linear Model and Anaerobic Model (called Biowin 1-7, respectively) of the BIOWIN v4.10 software. The results indicate that chemical sodium 2-[(1-oxododecyl)amino]ethanesulphonate is expected to be readily biodegradable.

In a supporting weight of evidence study from authoritative database (J Check, 2017) of read across chemical Sodium 2-(methyloleoylamino)ethane-1-sulphonate (CAS no.137-20-2) biodegradation test was performed by taking activated sludge as inoculums at 30 mg/L concentration. Biodegradation was analyzed by using three parameters that are BOD, TOC and test material analysis by UV vis . The initial concentration of read across chemical was 100 mg/L and study design was of standard type. After two weeks (14 days) of incubation read across chemical Sodium 2-(methyloleoylamino)ethane-1-sulphonate undergoes 75 % degradation by BOD parameter, 79 % degradation TOC parameter and  100% degradation by test material analysis by UV vis parameter. Thus based on percent biodegradability it is concluded that read aross chemical Sodium 2-(methyloleoylamino)ethane-1-sulphonate is readily biodegradable.

In another supporting weight of evidence study from same source as mentioned above ( J Check, 2017) of read across chemical Dodecyl sodium sulfate (CAS no. 151-21-3) biodegradation test was carried out by taking activated sludge as inoculums at 30 mg/L concentration. Biodegradation was analyzed by using three parameters that are O2 consumption (BOD), TOC removal and test material analysis by UV vis . The initial concentration of read across chemical was 100 mg/L and the equipments used in study was of standard type. After two weeks (14 days) of incubation read across chemical Dodecyl sodium sulfate undergoes 85 % degradation by O2 Consumption (BOD) parameter, 99.3 % degradation by both TOC removal parameter and test material analysis by UV vis parameter.Thus based on percent biodegradability it is concluded that read across chemical Dodecyl sodium sulfate is readily biodegradable.

On the basis of results of above mentioned studies for target chemical sodium 2-[(1-oxododecyl)amino]ethanesulphonate (CAS no.70609-66-4) ( from OECD QSAR tool box v3.3 and EPI suite) and supporting weight of evidence studies ( from J Check, 2017). It is concluded that the test chemical sodium 2-[(1-oxododecyl)amino]ethanesulphonate can be expected to be readily biodegradable.

Biodegradation in water and sediments:

Estimation Programs Interface (EPI Suite, 2017) prediction model was run to predict the half-life in water and sediment for the test compound sodium 2-[(1-oxododecyl)amino]ethanesulphonate (CAS No. 70609-66-4). If released in to the environment, 23 % of the chemical will partition into water according to the Mackay fugacity model level III and the half-life period of test chemical sodium 2-[(1-oxododecyl)amino]ethanesulphonate in water is estimated to be 15 days (360 hrs). The half-life (15 days estimated by EPI suite) indicates that the chemical is not persistent in water and the exposure risk to aquatic animals is moderate to low whereas the half-life period of test chemical sodium 2-[(1-oxododecyl)amino]ethanesulphonate in sediment is estimated to be 135 days (3240  hrs).  However as the percent release of test chemical sodium 2-[(1-oxododecyl)amino]ethanesulphonate into sediment is less than 1 % (i.e., reported as 0.215% ) indicates that test chemical sodium 2-[(1-oxododecyl)amino]ethanesulphonate is not persistant in sediments.

Biodegradation in soil:

The half-life period of test chemical sodium 2-[(1-oxododecyl)amino]ethanesulphonate (CAS No. 70609-66-4) in soil was estimated using Level III Fugacity Model by EPI Suite version 4.1 estimation database (EPI suite, 2017). If released into the environment, 76.2 % of the chemical will partition into soil according to the Mackay fugacity model level III. The half-life period of test chemical sodium 2-[(1-oxododecyl)amino]ethanesulphonate in soil is estimated to be 30 days (720 hrs). Based on this half-life value of test chemical sodium 2-[(1-oxododecyl)amino]ethanesulphonate, it is concluded that the chemical is not persistent in the soil environment and the exposure risk to soil dwelling animals is low.

Bioaccumulation:

Bioaccumulation: aquatic / sediment:

Two different predicted data for the target compound sodium 2-[(1-oxododecyl)amino]ethanesulphonate (CAS No. 70609-66-4) and supporting weight of evidence study for its read across chemical were reviewed for the bioaccumulation end point which are summarized as below:

In a prediction done by using BCFBAF Program (v3.00) model of Estimation Program Interface (EPI suite 2017) bio concentration factor (BCF) for sodium 2-[(1-oxododecyl)amino]ethanesulphonate (CAS No. 70609-66-4) estimated was 70.79L/kg wet-wt at 25 deg. c.

Another prediction done by using Bio-concentration Factor (v12.1.0.50374) of (ACD (Advanced Chemistry Development)/I-Lab predictive module, 2017) module the Bio-concentration Factor at range pH 1-14 of the chemical sodium 2-[(1-oxododecyl)amino]ethanesulphonate (CAS no.70609-66-4) estimated to be 1.0 dimensionless.

In a supporting weight of evidence study from Hazardous Substance Data Bank (HSDB, 2017) the BCF value of read across chemical Dodecyl sodium sulfate (CAS no.151-21-3) estimated was 71.0 dimensionless by using log Kow of 1.6 and regression derived equation and it is far less than 2000 criteria so it is concluded that read acroos chemical Dodecyl sodium sulfate is non bioaccumulative.

In another supporting weight of evidence study from same source as mentioned above (HSDB, 2017) the BCF value of read across chemical (dodecyloxy)sulfonic acid (CAS no.151-41-7) estimated was 71.0 dimensionless by using log Kow of 2.4 and regression derived equation and it is far less than 2000 criteria so it is concluded that read across chemical (dodecyloxy)sulfonic acid is non bioaccumulative.

On the basis of above results for target chemical sodium 2-[(1-oxododecyl)amino]ethanesulphonate (CAS No. 70609-66-4) (from EPI suite and ACD labs, 2017) and for its read across chemicals (From HSDB) it can be concluded that the BCF value of test substance sodium 2-[(1-oxododecyl)amino]ethanesulphonate ranges from 1 to 71.0 dimensionless which does not exceed the bioconcentration threshold of 2000, indicating that the chemical sodium 2-[(1-oxododecyl)amino]ethanesulphonate is expected to be non bioaccumulative in the food chain.

Transport and Distribution:

Adsorption / desorption:

Two different predicted data for the target compound of sodium 2-[(1-oxododecyl)amino]ethanesulphonate (CAS No. 70609-66-4) and supporting weight of evidence study for its read across chemical were reviewed for the Adsorption end point which are summarized as below.

The Soil Adsorption Coefficient i.e. Koc value of test chemical sodium 2-[(1-oxododecyl)amino]ethanesulphonate (CAS No. 70609-66-4) was estimated using EPI suite KOCWIN Program (v2.00) as 194.1 L/kg (log Koc= 2.2880) by means of MCI method at 25 deg. C. This log Koc value indicates that test chemical sodium 2-[(1-oxododecyl)amino]ethanesulphonate has low sorption to soil and therefore have moderate migration potential to ground water.

Another predicted Soil Adsorption Coefficient i.e Koc value of test substance sodium 2-[(1-oxododecyl)amino]ethanesulphonate (CAS no. 70609-66-4) was estimated using Adsorption Coefficient module (v12.1.0.50374) program of (ACD (Advanced Chemistry Development)/I-Lab predictive module, 2017) module as Koc 1.0 dimensionless (log Koc= 0.0). This log Koc value indicates that the test substance sodium 2-[(1-oxododecyl)amino]ethanesulphonate has negligible sorption to soil and therefore have rapid migration potential to groundwater.

In a supporting weight of evidence study from Hazardous Substance Data Bank (HSDB, 2017) the Koc value for read across chemical epsilon.-Caprolactam (CAS no.105-60-2) was estimated by using a structure estimation method based on molecular connectivity indices. The estimated Koc value was 57 dimensionless and log Koc is 1.7558 this log Koc value suggests that epsilon.-Caprolactam is expected to have low sorption to soil and sediment and therefore have moderate migration potential to ground water.

In another supporting weight of evidence study from same source as mentioned above (HSDB, 2017) the Koc value for read across chemical Lauric diethanolamide (CAS no.120-40-1) was estimated by using a structure estimation method based on molecular connectivity indices. The estimated Koc value was 52 dimensionless and log Koc is 1.7160 this log Koc value suggests that Lauric diethanolamide is expected to have low sorption to soil and sediment and therefore have moderate migration potential to ground water.

On the basis of above results for target chemical sodium 2-[(1-oxododecyl)amino]ethanesulphonate (CAS no. 70609-66-4) (from EPI suite and ACD labs 2017) and for its read across chemicals (From authoritative database HSDB) it can be concluded that the log Koc value of test substance sodium 2-[(1-oxododecyl)amino]ethanesulphonate ranges from 0 to 2.288 indicating that the chemical sodium 2-[(1-oxododecyl)amino]ethanesulphonate has negligible to low sorption to soil and sediment and therefore have rapid to moderate migration potential to ground water.