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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
activated sludge respiration inhibition testing
Type of information:
experimental study
Adequacy of study:
key study
Study period:
28 day biodegradation test (toxicity control)
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
comparable to guideline study with acceptable restrictions
Justification for type of information:
Although a 'guideline' study was used, the purpose of the study was to examine biodegradation.
A toxicity control group provided evidence that there is not microbial inhibition at concentrations in excess of water solubility

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2013
Report date:
2013

Materials and methods

Principles of method if other than guideline:
Evaluated as part of OECD 301 Ready Biodegradation study
GLP compliance:
yes (incl. QA statement)

Test material

Constituent 1
Chemical structure
Reference substance name:
1,4-dihydroxyanthraquinone
EC Number:
201-368-7
EC Name:
1,4-dihydroxyanthraquinone
Cas Number:
81-64-1
Molecular formula:
C14H8O4
IUPAC Name:
1,4-dihydroxy-9,10-dihydroanthracene-9,10-dione
Test material form:
not specified
Details on test material:
1,4-dihydroxyanthraquinone was supplied by Aldrich

Test solutions

Details on test solutions:
Tested at 25 mg/l as dispersion
Note that solublity in water is < 0.1 mg/l

Test organisms

Test organisms (species):
activated sludge of a predominantly domestic sewage

Study design

Test type:
static
Water media type:
freshwater
Limit test:
yes
Total exposure duration:
28 d
Remarks on exposure duration:
Tested over the duration of the biodegradation test

Test conditions

Test temperature:
22 C
pH:
Typically 7 - 8

Results and discussion

Effect concentrations
Key result
Duration:
28 d
Dose descriptor:
EC0
Effect conc.:
> 25 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
inhibition of total respiration

Applicant's summary and conclusion

Validity criteria fulfilled:
yes
Conclusions:
The absence of inhibition at concentrations in excess of solublity is considered an indication of low microbial toxicity.