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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to microorganisms

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Administrative data

Link to relevant study record(s)

Description of key information

NOEC (14 d) ≥ 15.5 mg/L (28% degradation, OECD 301B)

Key value for chemical safety assessment

Additional information

There is no respiration inhibition study available assessing the toxicity of Hexanedioic acid, di-C16-18 alkyl esters (CAS 92969-90-9) to activated sludge microorganisms. However, a standard ready biodegradability test conducted according to OECD guideline 301 B and GLP is available, whose toxicity control can be used to derive a NOEC. According to the Guidance on information requirements and chemical safety assessment (Chapter R.7b: Endpoint specific guidance, ECHA, 2017), a concentration can be used as NOEC value, if a compound degrades well in a ready biodegradability test, or does not inhibit the degradation of a positive control at a certain concentration.

The available study was performed including a toxicity control, which contains 15.5 mg/L of the test item and 40 mg/L of the reference material sodium acetate. The toxicity control attained 28% degradation after 14 days of incubation. Hence, the substance is not toxic to activated sludge microorganisms in the toxicity control and the test item concentration of 15.5 mg/L can be used as NOEC.