Registration Dossier
Registration Dossier
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EC number: 225-562-6 | CAS number: 4927-39-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Hazard for air
Hazard for terrestrial organisms
Hazard for predators
Additional information
Conclusion on classification
Classification was done according to the criteria described in the CLP regulation EC No 1272/2008, version 2016.
Acute aquatic hazard:
For classification acute toxicity data are available for aquatic invertebrates (Daphnia) and algae:
Daphnia: EC50 (48h) = 2.07 mg/L
Algae: ErC50 (72h) = 2.13 mg/L
The lowest EC50 value was observed for daphnia, which is hence the most sensitive species although the difference between daphnia and algae is minimal. According to Table 4.1.0 (a) the substance should not be classified for acute aquatic hazard, as the lowest EC50 (48h) for daphnia = 2.07 mg/L, is larger than the cut-off for classification of 1 mg/L.
Chronic aquatic hazard
For chronic classification, there are only chronic data available for one trophic level, algae. As described in Figure 4.1.1 in the CLP regulation (EC No 1272/2008, version 2016), the most stringent outcome of classification according to Table 4.1.0 (b) (i) or (ii) and (iii) should be used.
Table 4.1.0 (b) (i):
The substance is not readily biodegradable, hence Table 4.1.0 (b) (i) applies.
The 72h ErC10 for algae was 1.68 mg/L. Therefore, the substance should not be classified for chronic aquatic hazard. as the ErC10 is larger than the cut-off for classification of 1 mg/L.
Table 4.1.0 (b) (iii):
The substance is not readily biodegradable, the acute EC50 values for algae and invertebrates are both between 1 -10 mg/L, therefore the substance meets the criteria for classification for chronic aquatic hazard category 2.
Most stringent classification:
The conclusion of both assessment is that the substance should be classified for chronic aquatic hazard category 2.
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