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Physical & Chemical properties

Particle size distribution (Granulometry)

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Reference
Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Study period:
July 29, 2015
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
test procedure in accordance with generally accepted scientific standards and described in sufficient detail
Principles of method if other than guideline:
Laser light scattering. The test was performed according to the SOP - STR 071 (Hydro 2000S) protocol.
Particle size distribution was analysed using the Mastersizer 2000 tool, which uses the technique of laser diffraction to measure particle size. It measures intensity of light scattered as a laser beam passes through a dispersed particulate sample. The scattering pattern is then analysed to calculate particle size.
GLP compliance:
no
Type of method:
Laser scattering/diffraction
Type of distribution:
volumetric distribution
Percentile:
D50
Mean:
ca. 27.075 µm
Remarks on result:
other: after 2 minutes of ultrasonic treatment
Percentile:
D10
Mean:
ca. 7.792 µm
Remarks on result:
other: after 2 minutes of ultrasonic treatment.
Percentile:
D90
Mean:
ca. 82.991 µm
Remarks on result:
other: after 2 minutes of ultrasonic treatment.
Conclusions:
d(0.1): 7.792 µm
d(0.5): 27.075 µm
d(0.9): 82.991 µm
Executive summary:

Method

Particle size distribution was analysed using Mastersizer 2000 tool, which uses laser diffraction to measure particle size. This is obtained by measuring the intensity of light scattered as a laser beam passes through a dispersed particulate sample. The scattering pattern is then analysed to calculate particle size.

Result

Analysis carried out after 2 minutes of ultrasonic treatment:

d(0.1): 7.792 µm

d(0.5): 27.075 µm

d(0.9): 82.991 µm

Description of key information

MMD = 27.075 µm.

Additional information

Laser diffraction analysis.