Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 228-810-1 | CAS number: 6359-85-9
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 16.02.-20.02.2017
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
- Deviations:
- yes
- Remarks:
- A stock solution of the test substance should be prepared in n-octanol pre-saturated with water. Because of a low solubility of the test substance in this medium, the stock solution was prepared in water pre-saturated with n-octanol.
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- flask method
- Partition coefficient type:
- octanol-water
- Analytical method:
- high-performance liquid chromatography
- Key result
- Type:
- log Pow
- Partition coefficient:
- -0.8
- Temp.:
- 23 °C
- pH:
- 6.2
- Conclusions:
- Partition coefficient (log P) of the test substance Acid Yellow 25 determined by shake-flask method is: log Pow = -0.80 ± 0.04 (pH 6.2, 23°C)
- Executive summary:
The partition coefficient of the test substance Acid Yellow 25 was determined.For determination ofpartition coefficient was used the shake-flask method.
The test was performed according to the shake-flask method (OECD Test Guideline 107, Partition Coefficient (n-octanol/water): Shake Flask Method, Adopted 27 July 1995).
Partition coefficient (log P) of the test substance Acid Yellow 25 determined by shake-flask method is:
log POW= - 0.80 ± 0.04 (pH 6.2, 23.0°C)
Reference
Description of key information
The partition coefficient of the test substance Acid Yellow 25 was determined. For determination ofpartition coefficient was used the shake-flask method.
The test was performed according to theshake-flask method (OECD Test Guideline 107, Partition Coefficient (n-octanol/water): Shake Flask Method, Adopted 27 July 1995).
Only one study is available. GLP study.
Klimish score 1.
Key value for chemical safety assessment
- Log Kow (Log Pow):
- -0.8
- at the temperature of:
- 23 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
