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EC number: 203-470-7
CAS number: 107-18-6
Rabbits (3 males/group) were exposed for 24
hours to 25 - 200 mg/kg bw of 2-propen-1-ol (applied by injecting the
2-propen-1-ol though the occlusive dressing onto the surface of the skin
and sealing the puncture site with rubber cement). Apathy, along with
flushing of the skin, ataxia and diarrhoea were observed. On
histopathological examination, toxicities in the lungs (congestion),
liver (congestion and necrosis) and kidneys (heme casts and cloudy
swelling) were observed. The LD50 was 89 mg/kg bw.
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