Registration Dossier
Registration Dossier
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EC number: 203-470-7 | CAS number: 107-18-6
Genetic toxicity: in vitro
Administrative data
- Endpoint:
- in vitro gene mutation study in bacteria
- Remarks:
- Type of genotoxicity: gene mutation
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: peer-reviewed data
Data source
Reference
- Reference Type:
- other: database
- Title:
- Unnamed
- Year:
- 1 995
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 471 (Bacterial Reverse Mutation Assay)
- Deviations:
- not applicable
- GLP compliance:
- not specified
- Type of assay:
- bacterial reverse mutation assay
Test material
- Reference substance name:
- Allyl alcohol
- EC Number:
- 203-470-7
- EC Name:
- Allyl alcohol
- Cas Number:
- 107-18-6
- Molecular formula:
- C3H6O
- IUPAC Name:
- prop-2-en-1-ol
Constituent 1
Method
- Target gene:
- -
Species / strain
- Species / strain / cell type:
- S. typhimurium, other: TA 1535, TA 97, TA 98 and TA 100
- Metabolic activation:
- with and without
- Test concentrations with justification for top dose:
- Concentration: 0-333 µg/plate
Results and discussion
Test results
- Species / strain:
- S. typhimurium, other: TA 1535, TA 97, TA 98 and TA 100
- Metabolic activation:
- with and without
- Genotoxicity:
- negative
- Cytotoxicity / choice of top concentrations:
- no cytotoxicity
- Positive controls validity:
- valid
Applicant's summary and conclusion
- Conclusions:
- Under the conditions employed in the assay described in this report, the data suggest that the test article allyl alcohol shows no genetic toxicity.
Interpretation of results: negative.
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