Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 277-616-3 | CAS number: 73816-74-7
Particle size distribution (Granulometry)
Administrative data
Link to relevant study record(s)
- Endpoint:
- particle size distribution (granulometry)
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 7 - 27 February 2019
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- ISO 13320 (Particle size analysis - Laser diffraction methods)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 110 (Particle Size Distribution / Fibre Length and Diameter Distributions - Method A: Particle Size Distribution (effective hydrodynamic radius)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- Laser scattering/diffraction
- Type of distribution:
- volumetric distribution
- Specific details on test material used for the study:
- STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material: at dry and dark place between 5 - 30 degCelsius - Percentile:
- D10
- Mean:
- 14.2 µm
- St. dev.:
- 0.38
- Key result
- Percentile:
- D50
- Mean:
- 48.5 µm
- St. dev.:
- 0.64
- Percentile:
- D90
- Mean:
- 116.1 µm
- St. dev.:
- 1.15
- Conclusions:
- The test item Reactive Red 45:1 has a volumetric based median particle size D50 of 48.5 µm, which was determined by laser diffraction measurement.
- Endpoint:
- particle size distribution (granulometry)
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- 10.03.2016
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- ISO 13320 (Particle size analysis - Laser diffraction methods)
- Deviations:
- no
- Principles of method if other than guideline:
- The laser diffraction based on the Mie-scattering theory was selected for determination.
A representative sample, dispersed at an adequate concentration in a suitable liquid, is passed through the beam of a monochromatic light source (laser). A multi-element detector measures the light scattered by the particles at various angles and numerical values relating to the scattering pattern are then recorded for subsequent analysis. These numerical scattering values are then transformed, using an appropriate optical model and mathematical procedure (Mie theory), to yield the proportion of total volume to a discrete number of size classes forming a volumetric particle size distribution. - GLP compliance:
- no
- Other quality assurance:
- ISO/IEC 17025 (General requirements for the competence of testing and calibration laboratories)
- Type of method:
- Laser scattering/diffraction
- Type of particle tested:
- primary particle
- Type of distribution:
- volumetric distribution
- Mass median aerodynamic diameter:
- 23.6 µm
- Key result
- Percentile:
- D90
- Mean:
- 38.6 µm
- St. dev.:
- 1.4
- Key result
- Percentile:
- D10
- Mean:
- 12.2 µm
- St. dev.:
- 0.4
- Conclusions:
- See Executive Summary
- Executive summary:
The particle size distribution of the test substance, Reactive Red 45:1 was determined. The laser diffraction method was used.
The procedures used in the study were in accordance with:
Guidance Document on the Determination of Particle Size Distribution, Fibre Length and Diameter Distribution of Chemical Substances, EUR 20268 EN (2002).
Standard ISO 13320: 2009 Particle size analysis – Laser diffraction methods, First edition 2009-10-01.
Particle size distribution of test substance, Reactive Red 45:1, is characterized by the following table:
Determination
Median
(mm)
Diameter on Cumulative 90%
(µm)
Diameter on Cumulative 10%
(µm)
Span
(-)
Final result
23.6
38.6
12.2
1.1
Extended uncertainty
1.8
2.8
0.8
-
Referenceopen allclose all
Table No.1: Results of determination of particle size distribution
Determination |
Median (mm) |
Diameter on Cumulative 90% (µm) |
Diameter on Cumulative 10% (µm) |
Span (-) |
1 |
22.4 |
37.4 |
11.5 |
1.2 |
2 |
23.6 |
38.6 |
12.2 |
1.1 |
3 |
23.7 |
38.7 |
12.2 |
1.1 |
4 |
24.9 |
41.2 |
12.7 |
1.1 |
5 |
23.4 |
38.6 |
12.1 |
1.1 |
Average |
23.6 |
38.9 |
12.1 |
1.1 |
Standard deviation |
0.9 |
1.4 |
0.4 |
0.0 |
Extended uncertainty |
1.8 |
2.8 |
0.8 |
- |
Description of key information
The test item Reactive Red 45:1 has a volumetric based median particle size D50 of 48.5 µm, which was determined by laser diffraction measurement.
Additional information
The particle size is dependent on the production process. In the supporting study, a median particle size of 23.6 µm was observed.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
