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Physical & Chemical properties

Auto flammability

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Administrative data

Endpoint:
relative self-ignition temperature (solids)
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Documentation insufficient for assessment. No information on purity of the substance.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2007

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
EU Method A.16 (Relative Self-Ignition Temperature for Solids)
Deviations:
yes
Qualifier:
according to guideline
Guideline:
other: VDI Guideline 2263 Part 1: Autoignition-Testing as per Grewer
Deviations:
not specified
Qualifier:
according to guideline
Guideline:
other: ESCIS Expert Commission for Safety in the Swiss Chemical Industry, Booklet 1 ''Sicherheitstests fur Chemikalien''.
Deviations:
not specified
Principles of method if other than guideline:
Modifications to the EU A.16 Method: A heating rate of 1.0-1.2 deg C/min or 0.6 deg C/min is used instead of 0.5 deg C/min due to an alternative Swiss Chemical Industry method and technical restriction of the apparatus used. Cylindric wire baskets with 0.2 mm openings are used.
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
METHYL (1R,2R,4S)-2-[HEX-5-EN-1-YL(METHYL)CARBAMOYL]-4-({7-METHOXY-8-METHYL-2-[4-(PROPAN-2-YL)-1,3-THIAZOL-2-YL]QUINOLIN-4-YL}OXY)CYCLOPENTANECARBOXYLATE
EC Number:
922-147-8
Cas Number:
1042695-87-3
Molecular formula:
C32H41N3O5S
IUPAC Name:
METHYL (1R,2R,4S)-2-[HEX-5-EN-1-YL(METHYL)CARBAMOYL]-4-({7-METHOXY-8-METHYL-2-[4-(PROPAN-2-YL)-1,3-THIAZOL-2-YL]QUINOLIN-4-YL}OXY)CYCLOPENTANECARBOXYLATE
Test material form:
solid: particulate/powder
Details on test material:
- Name of test material (as cited in study reports): JNJ-39125593-AAA (T003019)
- Physical state: solid
- Appearance: white powder
Specific details on test material used for the study:
no data

Results and discussion

Relative self-ignition temperature (solids)
Remarks on result:
no self ignition observed under the test conditions

Any other information on results incl. tables

The sample is heated from room temperature (about 20 deg C) to ± 170 deg C (above the melting point).

The sample shows no self-heating to 400 deg C in the test run.

Applicant's summary and conclusion

Conclusions:
In conclusion, the tested substance T003019 is not auto-flammable according to the criteria as described in the guideline.