Registration Dossier
Registration Dossier
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EC number: 922-147-8 | CAS number: -
Density
Administrative data
- Endpoint:
- density, other
- Remarks:
- density
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 15 March - 25 April 2016
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 016
- Report date:
- 2016
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 109 (Density of Liquids and Solids)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.3 (Relative Density)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7300 (Density / Relative Density / Bulk Density)
- Deviations:
- no
- GLP compliance:
- yes
- Type of method:
- pycnometer method
Test material
- Reference substance name:
- methyl (1R,2R,4S)-2-[(hex-5-en-1-yl)(methyl)carbamoyl]-4-({7-methoxy-8-methyl-2-[4-(propan-2-yl)-1,3-thiazol-2-yl]quinolin-4-yl}oxy)cyclopentane-1-carboxylate
- EC Number:
- 922-147-8
- Cas Number:
- 1042695-87-3
- Molecular formula:
- C32H41N3O5S
- IUPAC Name:
- methyl (1R,2R,4S)-2-[(hex-5-en-1-yl)(methyl)carbamoyl]-4-({7-methoxy-8-methyl-2-[4-(propan-2-yl)-1,3-thiazol-2-yl]quinolin-4-yl}oxy)cyclopentane-1-carboxylate
- Test material form:
- solid: particulate/powder
- Details on test material:
- - Name of test material (as cited in study reports): JNJ-39125593-AAA (T003019)
- Physical state: solid
- Appearance: white powder
Constituent 1
- Specific details on test material used for the study:
- - Batch n°: M15FB2925
- Analytical purity: 99.5%
- Expiration date: 31 May 2017
- Storage condition: at room temperature protected from light
Results and discussion
Density
- Key result
- Type:
- density
- Density:
- 1.19 g/cm³
- Temp.:
- 20 °C
- Remarks on result:
- other: The difference between the results of the first and third measurements was < 0.02 g/cm³. According to the guideline, the density of the test item is therefore given as the mean value.
Any other information on results incl. tables
The density (ρ) of a substance is the quotient of its mass and its volume and is expressed in SI units of kg/m³.
The difference between the results of the measurements 1 and 3 was <0.02 g/cm³, while the coefficient of variation of measurement 2 was > 1.00%, therefore this measurement was not included for further calculations and the density of the test item is given as the mean value of measurement 1 and 3.
The individual density measurements were 1.187 g/cm³ (test 1) and 1.195 g/cm³ (test 3).
Applicant's summary and conclusion
- Conclusions:
- The density of the test item at 20ºC was 1.19 g/cm³ (1.19 x 10³ kg/m³).
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