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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

Additional information

All available experimental data on didocosyl sebacate (CAS 42233-75-0) performed according to internationally accepted guidelines indicate no evidence of acute and chronic toxicity to aquatic organisms. Data for all three trophic levels are available. No toxicity was observed up to the limit of water solubility in all available experimental studies. The water solubility of the test substance was determined to be 3.22E-04 g/L at 20 °C (EU Method A.6, column elution method). 

The short-term toxicity to fish was determined in a standard OECD guideline study according to OECD 203. No mortality was observed after 96 h resulting in a LL50 > 100 mg/L (i.e. above the water solubility limit). The same was recorded for the short-term toxicity to aquatic invertebrates and to aquatic algae. No immobilization of Daphnia magna (EL50 (48 h),>100 mg/L (nominal, limit test)) and no inhibition of growth of aquatic algae (EL50 (72 h),>100 mg/L (nominal)) were observed in experimental studies according to OECD guidelines up to the limit of water solubility.

The chronic data obtained from an algal growth inhibition study (NOELR (72 h), ≥100 mg/L (nominal))and a chronic study with aquatic invertebrates (NOEC (21 d): ≥100 mg/L (nominal) and LOEC (21 d): >100 mg/L (nominal)) are clearly above the limit of water solubility. As there was no sign that invertebrates are less sensitive than fish in the short-term tests, it cannot be expected that a long-term test with fish will generate different results then the available long-term test with aquatic invertebrates.

The degradation process in domestic sewage treatment plants is not suspected to be inhibited by the testsubstance. No effect on respiration rate was observed resulting in an EC50 of >1000 mg/L and NOEC was derived to be ≥1000 mg/L.