Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

Additional information

There is one study available investigating the terrestrial toxicity of didocosyl sebacate (CAS 42233 -75 -0) using earthworm as test organism. The study was performed according to OECD 207 (GLP). It did not result in significant effects on mortality at nominal concentration 1000 mg/kg soil dw. Therefore, the NOEC (14 d) is ≥ 1000 mg/kg soil dw. Exposure of the soil compartment is generally considered to be low. Indirect exposure via irrigation or atmospheric transport is considered to be negligible based on the physico-chemical properties (water solubility: 3.22E-04 g/L at 20 °C; vapour pressure: < 1.3E-03 Pa at 25 °C).

Available acute and chronic aquatic toxicity studies with fish, invertebrates, algae and microorganisms showed no adverse effects occurred in the range of the water solubility of the substance 3.22E-04 g/L at 20 °C). These results obtained support the assumption that the substance is likely to show no toxicity to terrestrial organisms as well.

The available data for toxicity to activated sludge microorganisms support the determination of a lack of toxicity to soil microorganisms. No inhibition of respiration rate of a microbial sewage treatment plant community was observed in the available study according to OECD 209. The Guidance Document (ECHA, 2014, page 136) states that a test on soil microbial activity will only be additionally necessary for a valid PNEC derivation if inhibition of sewage sludge microbial activity has occurred and this is clearly not the case. Based on the available information, effects on soil microorganisms are not expected to be of concern, and consequently, no further testing is required.