Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 247-644-0 | CAS number: 26386-88-9
Endpoint summary
Administrative data
Description of key information
No data were found for DPPA in the scientific literature.
The classification for acute toxicity is based on expert judgement and in particular considering the chemical category “Organophosphorus compounds” of the substance.
Organophosphorus compounds (OPs) can exert significant adverse effects in non-target species including humans. Because of the phosphorylation of acetylcholinesterase, they exert primarily a cholinergic toxicity, however, some can also cause a delayed polyneuropathy. Their relative toxicities are based on World Health Organization Guidelines and The Globally Harmonized Hazard System of Classification and Labeling of Chemicals (GHS).
The extremely toxic OPs are designed to Category 1, which are rated by their toxicity orally in the rat based on technical compound and generally show an LD50 of less than 5 mg/kg. The highly toxic OPs showing LD50 values of 5-50 mg/Kg are designed to Category 2. Their dermal and inhalation toxicity is also confirmed by GHS System.
The classification are been established according to information reported in the SDS of the supplier.
Key value for chemical safety assessment
Additional information
Justification for classification or non-classification
DPPA is classified for acute toxicity (oral) as Acute Tox. 3; H301.
DPPA is classified for acute toxicity (dermal) as Acute Tox. 2; H310.
DPPA is classified for acute toxicity (inhalation) as Acute Tox. 2; H330.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
