Registration Dossier
Registration Dossier
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EC number: 228-544-6 | CAS number: 6291-84-5
Endpoint summary
Administrative data
Description of key information
Study was scientifically not necessary for testing of this end point since pH of (3-aminopropyl)(methyl)amine (CAS No: 6291-84-5) was determined to be in 13.5 (From GESTIS), indicating that it was corrosive to skin hence the end point was considered for waiver.
Key value for chemical safety assessment
Skin sensitisation
Link to relevant study records
- Endpoint:
- skin sensitisation: in vivo (non-LLNA)
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- the study does not need to be conducted because the substance is a strong acid (pH ≤2.0) or base (pH =>11.5)
Reference
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (sensitising)
- Additional information:
Study was scientifically not necessary for testing of this end point since pH of (3-aminopropyl)(methyl)amine (CAS No: 6291-84-5) was determined to be in 13.5 (From GESTIS), indicating that it was corrosive to skin hence the end point was considered for waiver.
Respiratory sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no study available
Justification for classification or non-classification
Study was scientifically not necessary for testing of this end point since pH of (3-aminopropyl)(methyl)amine (CAS No: 6291-84-5) was determined to be in 13.5 (From GESTIS), indicating that it was corrosive to skin hence the end point was considered for waiver.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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