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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acidity / alkalinity
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: according to the method of YOUNG

Data source

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: method of YOUNG
Version / remarks:
J.R. Young et al., Toxic. in Vitro Vol. 2, No. 1, pp. 19 -26, 1988
GLP compliance:
no

Reagents

Reagent:
NaOH solution

Titration of acidity and alkalinity

Details on titrant used:
- Titer of titrant used: 1 m sodium hydroxide solution

Results and discussion

pH value
pH value:
2.3
Remarks on result:
other: initial pH of 10 % aqueous solution

Any other information on results incl. tables

2 measurements were performed:

run no 1: pH 2.3, titration volume to pH 4.0: 0.955 mL for 2.0877 g of the 10 % test substance solution, resulting in 18.3 g NaOH/100 g test substance

run no 2: pH 2.3, titration volume to pH 4.0: 2.186 mL for 4.8412 g of the 10 % test substance solution, resulting in 18.1 g NaOH/100 g test substance

 

mean: 18.2 g NaOH/100 g test substance

Applicant's summary and conclusion

Conclusions:
Based on the determined acid reserve and calculation according to YOUNG the test substance can be assumed to be irritant.