Registration Dossier

Diss Factsheets

Administrative data

Description of key information

No acute oral and inhalation toxicity studies were available for the registered substance.

In accordance with Column 2 of REACH Annex VIII, the acute toxicity study via the oral route (required in Section 8.5.1) does not need to be conducted as the substance is classified as corrosive.

In accordance with Column 2 of REACH Annex VIII, the acute toxicity study via the inhalation route (required in Section 8.5.2) does not need to be conducted as the substance is classified as corrosive.

In accordance with Column 2 of REACH Annex VIII, the acute toxicity study via the dermal route (required in Section 8.5.3) does not need to be conducted as the substance is classified as corrosive.

Key value for chemical safety assessment

Acute toxicity: via oral route

Endpoint conclusion
Endpoint conclusion:
no study available

Acute toxicity: via inhalation route

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed

Acute toxicity: via dermal route

Endpoint conclusion
Endpoint conclusion:
no study available

Additional information

No acute oral, inhalation or dermal toxicity studies were available for the registered substance.

The supporting acute oral study on dichloro(3-chloropropyl)methylsilane (CAS 7787-93-1) is included to support the data waiver for repeated dose toxicity and reproductive and developmental toxicity testing via the oral route (see Section 5.6.4 of the Chemical Safety Report).

The supporting acute inhalation studies on trichloro(methyl)silane, trichloro(ethyl)silane and trichloro(propyl)silane are included to support the data waiver for repeated dose toxicity testing via the inhalation route (see Section 5.6.4 of the Chemical Safety Report).

Justification for classification or non-classification

No acute toxicity studies have been performed due to the corrosive nature of the substance.

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