Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
relative density
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2016
Report date:
2016

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
OECD Guideline 109 (Density of Liquids and Solids)
Version / remarks:
adopted 02. Oct. 2012
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.3 (Relative Density)
Version / remarks:
30 May 2008
Deviations:
no
Qualifier:
according to guideline
Guideline:
other: SOP 118 009 14 “Bestimmung der Dichte von Feststoffen mit Pyknometer“
Version / remarks:
edition 7, valid from 03. Dec. 2012
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
pycnometer method

Test material

Constituent 1
Chemical structure
Reference substance name:
Pyridine-2-carbaldehyde oxime
EC Number:
212-849-6
EC Name:
Pyridine-2-carbaldehyde oxime
Cas Number:
873-69-8
Molecular formula:
C6H6N2O
IUPAC Name:
pyridine-2-carbaldehyde oxime
Test material form:
solid: particulate/powder

Results and discussion

Densityopen allclose all
Key result
Type:
density
Density:
1.301 g/cm³
Temp.:
20 °C
Remarks on result:
other: mean of two independent determinations; standard deviation: ± 0.0096 g/cm3; ± 0.4 °C
Key result
Type:
relative density
Density:
1.301 other: no unit
Temp.:
20 °C
Remarks on result:
other: mean of two independent determinations; standard deviation: ± 0.0096; ± 0.4 °C; relative standard deviation 0.74%

Applicant's summary and conclusion

Conclusions:
Density = 1.3012 ± 0.0096 g/cm3 at 20 ± 0.4 °C;
Relative density = 1.3012 at 20 °C.
The study was performed according to OECD TG109 and EU Method A.3 without deviations and therefore reliability of Klimisch 1 has been assigned.
Executive summary:

The density of the test substance was determined in a GLP test according to OECD 109 resp. EU A.3. Using the pycnometer method, a density of 1.3012 ± 0.0096 g/cm3at 20 ± 0.4 °C was measured; the relative density of the test substance has the same number value, but no unit. This value is the mean of two independent determinations; standard deviation was 0.0096 g/cm3. Correspondence of the values is good, the study is therefore considered valid.