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Administrative data

Endpoint:
oxidising solids
Type of information:
experimental study
Adequacy of study:
key study
Study period:
1991-10-22 to 1991-11-05
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1991
Report date:
1991

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
EU Method A.17 (Oxidising Properties (Solids))
Deviations:
no
GLP compliance:
yes (incl. QA statement)

Test material

Constituent 1
Chemical structure
Reference substance name:
3-(2-{4-[(Z)-(2,4-DIFLUOROPHENYL)(HYDROXYIMINO)METHYL]PIPERIDIN-1-YL}ETHYL)-2-METHYL-6,7,8,9-TETRAHYDRO-4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE
EC Number:
603-689-1
Cas Number:
132961-05-8
Molecular formula:
C23H28F2N4O2
IUPAC Name:
3-(2-{4-[(Z)-(2,4-DIFLUOROPHENYL)(HYDROXYIMINO)METHYL]PIPERIDIN-1-YL}ETHYL)-2-METHYL-6,7,8,9-TETRAHYDRO-4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE
Test material form:
solid: particulate/powder
Specific details on test material used for the study:
Name of test material (as cited in study report): T001624
- Physical state: powder
- Analytical purity: 94.0 %
- Lot/batch No.: 00096264
- Lotidentification: RT001624BEA011
- Storage condition of test material: at room temperature

Study design

Contact with:
powdered cellulose

Results and discussion

Test results (Oxidising solids)open allclose all
Sample tested:
reference mixture (not specified)
Parameter:
maximum burning rate
Result:
1.02 mm/s
Sample tested:
test mixture (not specified)
Parameter:
maximum burning rate
Result:
0.725 mm/s
Remarks on result:
other: Maxim burning rate obtained for 60% weight of the substance.

Any other information on results incl. tables

The maximum burning rate of the substance/cellulose mixture is at 60% substance: 0.725 mm/s. But the substance/kieselguhr mixture also shows a burning behaviour with a maximum burning rate of 0.980 mm/s at a 70% substance content. As kieselguhr is an inert material, the combustion of the subtance/cellulose mixture is not due to the oxidising properties of the substance but is caused by changed burning characteritics of the mixture.

Applicant's summary and conclusion

Interpretation of results:
GHS criteria not met
Conclusions:
The substance T006124 has no oxidising properties.