Registration Dossier
Registration Dossier
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EC number: 946-134-1 | CAS number: 164651-56-3
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
EC50 = 2.3 mg/l.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 2.3 mg/L
Additional information
No studies conducted on the substance in itself are available, nevertheless studies conducted with an analogue molecule (Similar Substance 01) were considered to complete the assessment. Further information are reported in the Read Across justification attached to section 13.
In order to determine the short-term toxicity to aquatic invertebrates, the substance under registration was tested on Daphnia sp. according to OECD Guideline 202. The concentrations tested were: 1.5/0.3/0.9/3.4/8.2/4.4/4.7/11.4/28.2 mg test article /l based on analytical results. The nominal concentrations were 1.0/1.8/3.2/5.8/10/18/32/58 and 100 mg test article /l.
The EC50 was determined in two ways: graphically, interpolating the point plotted on a graph; and statistically, calculating with the "probit model" method. The EC50 at 48 hours were 1.6 and 2.3 mg/l respectively. The EC50 value obtained statistically has been used as reference due to the more reliability of the method.
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