Registration Dossier
Registration Dossier
Diss Factsheets
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EC number: 204-340-2 | CAS number: 119-64-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

PBT assessment
Administrative data
PBT assessment: overall result
- PBT status:
- the substance is not PBT / vPvB
- Justification:
Tetrahydronaphthalene was degraded by 81% in the BODIS test after 28 days (Hüls AG 1989). The substance can therefore be assessed as ultimately biodegradable.
The BCF was determined by QSAR estimation (Degussa, 2004). Considering the measured Log Pow of 3.78 the BCF for fish was 162.4 L/kg (calculated with BCFWIN v 2.14 as integrated in EPIWIN V3.10) and 326 and 1500 for Pimephales promelas and Leuciscus idus, respectively (according to EU Technical Guidance Document on Risk Assessment of Chemical Substances following European Regulations and Directives, 2nd Edition (2003)).
Furthermore, animal experiments in rats investigating toxicokinetics upon single or repeated oral dosing indicated rapid absorption, and elimination mainly via urine. Tetrahydronaphthalene is metabolized by hydroxylation at the non-aromatic portion of the molecule. The metabolites are excreted mainly (generally > 90 %) as glucuronides. According to mammalian toxicity data, tetrahydronaphthalene is not classified as very toxic (T+), Toxic (T) or harmful (Xn) and does not carry the risk phrases R48, R60, R62, R63 or R64. R48 or R60-R64.
Therefore, tetrahydronaphthalene is not expected to accumulate in the environment and no bioaccumulation is expected.
Tetrahydronaphthalene is not classified as mutagenic or toxic for reproduction and it is not classified as T, R48 or Xn, R48 according to Directive 67/548/EEC. Long-term aquatic toxicity data are available for Desmodesmus subspicatus. The data indicate a NOEC of 3.8 mg/L, which is above the screening criteria of Annex XIII of the REACH Regulation. The lowest acute L/EC50 value is > 0.1 mg/L, indicating that the substance is not considered to meet potentially the T-criterion. Therefore, tetrahydronaphthalene does not fulfil the T-criterion.
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