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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Classification & Labelling & PBT assessment

PBT assessment

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Administrative data

PBT assessment: overall result

PBT status:
the substance is not PBT / vPvB

Tetrahydronaphthalene was degraded by 81% in the BODIS test after 28 days (Hüls AG 1989). The substance can therefore be assessed as ultimately biodegradable.


The BCF was determined by QSAR estimation (Degussa, 2004). Considering the measured Log Pow of 3.78 the BCF for fish was 162.4 L/kg (calculated with BCFWIN v 2.14 as integrated in EPIWIN V3.10) and 326 and 1500 for Pimephales promelas and Leuciscus idus, respectively (according to EU Technical Guidance Document on Risk Assessment of Chemical Substances following European Regulations and Directives, 2nd Edition (2003)).


Furthermore, animal experiments in rats investigating toxicokinetics upon single or repeated oral dosing indicated rapid absorption, and elimination mainly via urine. Tetrahydronaphthalene is metabolized by hydroxylation at the non-aromatic portion of the molecule. The metabolites are excreted mainly (generally > 90 %) as glucuronides. According to mammalian toxicity data, tetrahydronaphthalene is not classified as very toxic (T+), Toxic (T) or harmful (Xn) and does not carry the risk phrases R48, R60, R62, R63 or R64. R48 or R60-R64.


Therefore, tetrahydronaphthalene is not expected to accumulate in the environment and no bioaccumulation is expected.


Tetrahydronaphthalene is not classified as mutagenic or toxic for reproduction and it is not classified as T, R48 or Xn, R48 according to Directive 67/548/EEC. Long-term aquatic toxicity data are available for Desmodesmus subspicatus. The data indicate a NOEC of 3.8 mg/L, which is above the screening criteria of Annex XIII of the REACH Regulation. The lowest acute L/EC50 value is > 0.1 mg/L, indicating that the substance is not considered to meet potentially the T-criterion. Therefore, tetrahydronaphthalene does not fulfil the T-criterion.