Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Key value for chemical safety assessment

Genetic toxicity in vitro

Description of key information

Similar substance 1 is not mutagenic or clastogenic in guideline 471 in vitro studies; i.e. bacterial reverse mutation study.

A detailed description of the read across chosen is reported in section 13.

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (negative)

Additional information

Additional information from genetic toxicity in vitro:

Similar substance 1 was examined for point mutations in bacteria using the Ames test according to OECD TG 471 under GLP conditions. 5 strains (S. typhimurium TA 1535, TA 1537, TA 98, TA 100 and TA 102) and concentrations up to 5000 µg/plate in the presence and absence of a metabolic activation system were investigated. The tested substance is considered negative in this test.

Justification for classification or non-classification

Similar substance 1 is not mutagenic or clastogenic in guideline in vitro studies; i.e. bacterial reverse mutation study.

A detailed description of the read across chosen is reported in section 13.