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Toxicological information

Sensitisation data (human)

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Administrative data

Endpoint:
sensitisation data (humans)
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: publication does not give sufficient experimental details

Data source

Reference
Reference Type:
publication
Title:
Bioavailability of rubber accelerators in rubber gloves and patch test reactivity
Author:
Knudsen, B., B.; et al.
Year:
2000
Bibliographic source:
Dermatol. Beruf Umwelt 48, Heft 4, 127-133

Materials and methods

Type of sensitisation studied:
skin
Study type:
other: study with dermatitis patients
Principles of method if other than guideline:
other: patch test with dermatitis patients
GLP compliance:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
zinc-mercaptobenzothiazole

Method

Type of population:
general
Route of administration:
dermal

Results and discussion

Results of examinations:
8/25 patients with postive patch-test reactions

Applicant's summary and conclusion