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EC number: 227-579-4 | CAS number: 5895-46-5
Table1 Mean OD540Values and Viabilities for the Negative Control, Positive Control Material and Test Material
Mean OD540of duplicate tissues
Relative mean viability (%)
Negative Control Material
Positive Control Material
*= The mean viability of the negative control tissues is set at 100%
Table2 Qualitative Evaluation of Tissue Viability (MTT uptake visual evaluation)
MTT Visual Scoring Scheme of SkinEthic Tissues
- = Blue tissue (viable)
+ = Blue/white tissue (semi-viable)
++ = Tissue completely white (dead)
In the in vitro skin corrosivity potential test with the EpiskinTM reconstituted human epidermis model (according to OECD 431) dineodymium tricarbonate was tested for 3, 60, and 240 minutes. The EpiskinTM model is able to distinguish between corrosive and non-corrosive chemicals for purposed of UN and EU labeling. Duplicate tissues were treated. At the end of exposure viability was assessed based on the MTT reduction in the test material treated tissues relative to the negative control tissues. The relative mean viabilitiy of the test material treated materials was 100.4%, 107.4%, and 91.4% after 240, 60, and 3 minutes. The test material was considered to be NON-Corrosive to the skin and accredited the EU risk phrase of NO label and a UN packing group Non-Corrosive.
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