L-4-hydroxyproline

Auto flammability

Link to relevant study record(s)

Reference

Endpoint:

relative self-ignition temperature (solids)

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2017-05-15 to 2017-07-06

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

EU Method A.16 (Relative Self-Ignition Temperature for Solids)

Version / remarks:

2008

Deviations:

no

GLP compliance:

no

Specific details on test material used for the study:

SOURCE OF TEST MATERIAL
- Source and lot/batch No.of test material: Thai Hakko Biotechnologies Co., Ltd. / batch 160006
- Expiration date of the lot/batch: retest date 2018-02-22
- Purity test date: 2016-03-08

STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material: 10 - 25 °C in a tightly closed container, stored in a dry and well ventilated place
- Stability under test conditions: stable
- Solubility and stability of the test substance in the solvent/vehicle: highly soluble
- Reactivity of the test substance with the solvent/vehicle of the cell culture medium: n.a.

Key result

Remarks on result:

no self ignition observed under the test conditions

Conclusions:

L-4-Hydroxyproline is considered to be not auto-flammable,

Executive summary:

The purpose of the study was to provide preliminary information on the auto flammability of L-4 Hydroxyproline at elevated temperatures.

Using a linear increase in temperature of 0.5 °C/min up to about 400 °C, the test item L-4-Hydroxyproline showed no self-ignition reaction. At the end of measurement the test item was solid and the colour was black.

In conclusion, the test item L-4-Hydroxyproline is considered to be not auto-flammable, according to the criteria as described in the guideline

Description of key information

L-4-Hydrxyproline is considered to be not auto-flammable