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EC number: 200-091-9 | CAS number: 51-35-4
Particle size distribution (Granulometry)
Administrative data
Link to relevant study record(s)
- Endpoint:
- particle size distribution (granulometry)
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2017-07-13 to 2017-08-03
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 110 (Particle Size Distribution / Fibre Length and Diameter Distributions) - Method B: Fibre Length and Diameter Distributions
- Qualifier:
- according to guideline
- Guideline:
- ISO 13320 (Particle size analysis - Laser diffraction methods)
- Version / remarks:
- 2009
- Qualifier:
- according to guideline
- Guideline:
- other: CIPAC MT 187
- GLP compliance:
- no
- Type of method:
- Laser scattering/diffraction
- Type of particle tested:
- primary particle
- Type of distribution:
- volumetric distribution
- Specific details on test material used for the study:
- SOURCE OF TEST MATERIAL
- Source and lot/batch No.of test material: Thai Kyowa Biotechnologies Co. Ltd. / batch 160006
- Expiration date of the lot/batch: 2018-02-22
- Purity test date:2016-03-08
STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material: Ambient temperature (15 °C - 25 °C), protected from light
- Stability under test conditions: stable
-
TREATMENT OF TEST MATERIAL PRIOR TO TESTING
- Treatment of test material prior to testing: none - Key result
- Percentile:
- other: L50
- Mean:
- 274.1 µm
- Remarks on result:
- other: St. dev. not reported
- Percentile:
- other: L10
- Mean:
- 59.1 µm
- Remarks on result:
- other: St. dev. not reported
- Percentile:
- other: L90
- Mean:
- 663.8 µm
- Remarks on result:
- other: St. dev. not reported
- Conclusions:
- The median particle size L50 of the test item deduced from the particle size distributions was
274.1 µm.
The particle size L10 of the test item deduced from the particle size distributions was
59.1 µm.
The particle size L90 of the test item deduced from the particle size distributions was
663.8 µm. - Executive summary:
The particle size distribution of L-4-Hydroxyproline was determined by laser diffraction in a study according to OECD 110.
The median particle size L50 of the test item deduced from the particle size distributions was
274.1 µm.
The particle size L10 of the test item deduced from the particle size distributions was
59.1 µm.
The particle size L90 of the test item deduced from the particle size distributions was
663.8 µm.
Reference
Description of key information
The median particle size L50 of the test item deduced from the particle size distributions was
274.1 µm.
The particle size L10 of the test item deduced from the particle size distributions was
59.1 µm.
The particle size L90 of the test item deduced from the particle size distributions was
663.8 µm.
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