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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to fish

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short-term toxicity to fish
Type of information:
calculation (if not (Q)SAR)
Adequacy of study:
key study
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
accepted calculation method
Principles of method if other than guideline:
Accepted calculation method
GLP compliance:
Analytical monitoring:
not required
Test organisms (species):
other: Fathead minnow
Test type:
other: Calculation
Dose descriptor:
Effect conc.:
10 700 mg/L
Conc. based on:
test mat.
Basis for effect:
mortality (fish)
Remarks on result:
other: Calculation
Validity criteria fulfilled:
LC50 as predicted by TopKat v6.1: 10700 mg/L.
Executive summary:

LC50 as predicted by TopKat v6.1: 10700 mg/L

short-term toxicity to fish
Data waiving:
study scientifically not necessary / other information available
Justification for data waiving:

Description of key information

The results from calculations with 3 accepted calculation methods show that the substance has a very low acute aquatic toxicity. Experimnetal data on the acute aquatic toxicity to Daphnia and algae are available. According to OECD 126 threshold concentration will have to be derived from acute algae and daphnia data. Therefore and for the sake of animal welfare an experimental study referring to acute aquatic toxicity to fish is not conducted.

The lowest calculated value is used as LC50.

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Dose descriptor:
Effect concentration:
10 700 mg/L

Additional information