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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
extended one-generation reproductive toxicity - basic test design (Cohorts 1A, and 1B without extension)
Data waiving:
study scientifically not necessary / other information available
Justification for data waiving:
other:

Data source

Referenceopen allclose all

Reference Type:
review article or handbook
Title:
Extrapolation from results of animal studies to humans for the endpoint male fertility.
Author:
BAuA
Year:
2003
Bibliographic source:
Forschungsbericht Fb 984
Reference Type:
publication
Title:
A retrospective analysis of the added value of the rat two-generation reproductive toxicity study versus the rat subchronic toxicity study.
Author:
Janer G, Hakkert BC, Piersma, AH, Vermeire T, Slob W
Year:
2007
Bibliographic source:
Reproductive Toxicol 24: 103-113
Reference Type:
publication
Title:
Some aspects relating to the evaluation of the effects of chemicals on male fertility.
Author:
Mangelsdorf I, Buschmann J, Orthen B
Year:
2003
Bibliographic source:
Reg Toxicol Pharmacol 37: 356-369
Reference Type:
other: US EPA TSCA 8(e) submission
Title:
Unnamed
Year:
1990
Report date:
1967
Reference Type:
publication
Title:
2-DIETHYLAMINOETHANOL CAS N°:100-37-8, SIDS Initial Assessment Report For SIAM 15
Author:
OECD SIDS
Year:
2004
Bibliographic source:
UNEP Publications
Reference Type:
other: US EPA TSCA 8(e) submission
Title:
Unnamed
Year:
1966
Report date:
1966
Reference Type:
study report
Title:
Unnamed
Year:
1990
Report date:
1990
Reference Type:
other: US EPA TSCA 8(e) submission
Title:
Unnamed
Year:
1990
Reference Type:
publication
Title:
Evaluation of the inhalation toxicity of diethylethanolamine (DEEA) in rats.
Author:
Hinz, JP et al.
Year:
1992
Bibliographic source:
Fundam. Appl. Toxicol. 18: 418-424

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 443 (Extended One-Generation Reproductive Toxicity Study)

Results and discussion

Overall reproductive toxicity

Reproductive effects observed:
not specified

Applicant's summary and conclusion