Isoleucine, N-(1-oxohexadecyl)-

Surface tension

Link to relevant study record(s)

Reference

Endpoint:

surface tension

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Qualifier:

according to guideline

Guideline:

OECD Guideline 115 (Surface Tension of Aqueous Solutions)

Version / remarks:

OECD Guideline No. 115 (1995)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

ring method

Specific details on test material used for the study:

SOURCE OF TEST MATERIAL
- Source and lot/batch No.of test material: Batch 1700000153
- Expiration date of the lot/batch: 25 January 2020
- Purity test of the test item material: 98,1%
STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material: The test item was stored in darkness at room temperature.

Key result

Surface tension:

ca. 56.4 mN/m

Temp.:

20.1 °C

Conc.:

1.35 mg/L

Remarks on result:

other: The test item was considered as surface-active in the experimental conditions used

Verification with distilled water:

Temperature (°C)	20.3
Time	Surface tension (mN/m)
After 23 s	71.20
After 85 s	71.22
After 147 s	71.23
Mean result	71.2

The mean surface tension of distilled water is 71.2 mN/m at 20.3°C, mesurement vessel was considered to be clean and ready for use.

Mesurements on the test item diluted at 1.35 mg/L in distilled water:

Assay No.	4
Temperature (°C)	20.1
Time	Surface tension (mN/m)
After 23 s	55.12
After 85 s	54.74
After 145 s	54.56
After 206 s	54.45
After 266 s	54.35
After 326 s	54.28
Mean result	54.4

 

Assay No.	5
Temperature (°C)	20.2
Time	Surface tension (mN/m)
After 22 s	57.48
After 82 s	57.13
After 142 s	56.96
After 203 s	56.85
After 263 s	56.74
After 324 s	56.65
Mean result	56.8

Assay No.	7
Temperature  (°C)	20.1
Time	Surface tension (mN/m)
After 23 s	59.16
After 83 s	58.47
After 144 s	58.47
After 204 s	58.31
After 265 s	58.18
After 326 s	58.08
After 386 s	57.99
Mean result	58.1

Remark : the assays Nos. 1, 2 and 3 were performed but the results were not satisfactory because the values didn't stabilise. The assay No. 6 was performed but it was not taken into account due to the fact that the result was too far from others.

Conclusions:

The mean surface tension of the test item diluted at 1.35 mg/L (90% of its hydrosolubility) in distilled water at 20.1°C was 56.4 mN/m.
The test item was considered as surface-active in the experimental conditions used.

Executive summary:

In compliance with Regulation (EC) No. 1907/2006, Council Regulation (EC) No. 440/2008 EC A.5. method (2008) and OECD Guideline No.115 (1995):

The objective of the test was to determine the surface tension of the test item at 90% of its hydrosolubility in distilled water. The surface tension is defined as the free surface enthalpy per unit of area and is expressed in mN/m.

The mean surface tension of the test item diluted at 1.35mg/L (90% of its hydrosolubility) in distilled water at 20.1°C was 56.4 mN/m.

The test item was considered as surface-active in the experimental conditions used.

Description of key information

In compliance with Regulation (EC) No. 1907/2006, Council Regulation (EC) No. 440/2008 EC A.5. method (2008) and OECD Guideline No.115 (1995):

The objective of the test was to determine the surface tension of the test item at 90% of its hydrosolubility in distilled water. The surface tension is defined as the free surface enthalpy per unit of area and is expressed in mN/m.

The mean surface tension of the test item diluted at 1.35mg/L (90% of its hydrosolubility) in distilled water at 20.1°C was 56.4 mN/m.

The test item was considered as surface-active in the experimental conditions used.

Key value for chemical safety assessment

Surface tension:

56.4

in mN/m at 20°C and concentration in mg/L:

1.35