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EC number: 218-880-1 | CAS number: 2273-43-0
Endpoint summary
Administrative data
Description of key information
Biodegradation in water
Estimation Programs Interface Suite (2017) was run to predict the biodegradation potential of the test compound Butylstannonic acid (CAS no. 2273 -43 -0) in the presence of mixed populations of environmental microorganisms. The biodegradability of the substance was calculated using seven different models such as Linear Model, Non-Linear Model, Ultimate Biodegradation Timeframe, Primary Biodegradation Timeframe, MITI Linear Model, MITI Non-Linear Model and Anaerobic Model (called as Biowin 1-7, respectively) of the BIOWIN v4.10 software. The results indicate that chemical Butylstannonic acid is expected to be not readily biodegradable.
Biodegradation in water and sediment
Estimation Programs Interface (2017) prediction model was run to predict the half-life in water and sediment for the test compound Butylstannonic acid (CAS No. 2273 -43 -0). If released in to the environment, 26 % of the chemical will partition into water according to the Mackay fugacity model level III and the half-life period of test chemical in water is estimated to be 15 days (360 hrs). The half-life (15 days estimated by EPI suite) indicates that the chemical is not persistent in water and the exposure risk to aquatic animals is low whereas the half-life period of test chemical Butylstannonic acid in sediment is estimated to be 135 days (3240 hrs). However as the percentage release of test chemical into sediment is less than 1 %(i.e., reported as 0.249) indicates that test chemical Butylstannonic acid is not persistent in sediment as well.
Biodegradation in soil
The half-life period of test chemical Butylstannonic acid(CAS No.2273 -43 -0) in soil was estimated using Level III Fugacity Model by EPI Suite version 4.1 estimation database (2017). If released into the environment, 72.3 % of the chemical will partition into soil according to the Mackay fugacity model level III. The half-life period of test chemicalButylstannonic acidin soil is estimated to be 30 days (720 hrs). Based on this half-life value of test chemicalButylstannonic acid, it is concluded that the chemical is not persistent in the soil environment and the exposure risk to soil dwelling animals is low.
Additional information
Biodegradation in water
Predicted data for the target compoundButylstannonic acid(CAS No. 2273-43-0) and various supporting weight of evidence studies for its structurally and functionally similar read across substance were reviewed for the biodegradation end point which are summarized as below:
In a prediction using the Estimation Programs Interface Suite (2017), the biodegradation potential of the test compoundButylstannonic acid(CAS No. 2273-43-0) in the presence of mixed populations of environmental microorganisms was estimated.The biodegradability of the substance was calculated using seven different models such as Linear Model, Non-Linear Model, Ultimate Biodegradation Timeframe, Primary Biodegradation Timeframe, MITI Linear Model, MITI Non-Linear Model and Anaerobic Model (called as Biowin 1-7, respectively) of the BIOWIN v4.10 software. The results indicate that chemicalButylstannonic acidis expected to be not readily biodegradable.
In a supporting weight of evidence study from authoritative database (2017), the test chemical was subjected to biodegradation test by taking activated sludge as inoculums at 30 mg/L concentration. Biodegradation was analysed by using BOD and HPLC parameters. The initial concentration of test chemical taken was 100 mg/L. Percent biodegradation of test chemical was determined to be 0.0 % by BOD parameter and 1.0 % by HPLC parameter in 28 days. On the basis of percent degradation value it is concluded that test chemical is not readily biodegradable.
For the test chemical,biodegradation study was conducted for 28 days for evaluating the percentage biodegradability of test substance. Activated sludge was used as a test inoculums for the study. Concentration of inoculum i.e, sludge used was 30 mg/l and initial test substance conc. used in the study was 100 mg/l, respectively. The percentage degradation of test substance was determined to be 36 and 48% by BOD and GC parameter in 28 days. Thus, based on percentage degradation, test chemical is considered to be not readily biodegradable in nature.
On the basis of above results for target chemical Butylstannonic acid (from modelling database, 2017), it can be concluded that the test substance Butylstannonic acid can be expected to be not readily biodegradable in nature.
Biodegradation in water and sediment
Estimation Programs Interface (2017) prediction model was run to predict the half-life in water and sediment for the test compound Butylstannonic acid (CAS No. 2273 -43 -0). If released in to the environment, 26 % of the chemical will partition into water according to the Mackay fugacity model level III and the half-life period of test chemical in water is estimated to be 15 days (360 hrs). The half-life (15 days estimated by EPI suite) indicates that the chemical is not persistent in water and the exposure risk to aquatic animals is low whereas the half-life period of test chemical Butylstannonic acid in sediment is estimated to be 135 days (3240 hrs). However as the percentage release of test chemical into sediment is less than 1 %(i.e., reported as 0.249) indicates that test chemical Butylstannonic acid is not persistent in sediment as well.
Biodegradation in soil
The half-life period of test chemicalButylstannonic acid(CAS No.2273 -43 -0) in soil was estimated using Level III Fugacity Model by EPI Suite version 4.1 estimation database (2017). If released into the environment, 72.3 % of the chemical will partition into soil according to the Mackay fugacity model level III. The half-life period of test chemicalButylstannonic acidin soil is estimated to be 30 days (720 hrs). Based on this half-life value of test chemicalButylstannonic acid, it is concluded that the chemical is not persistent in the soil environment and the exposure risk to soil dwelling animals is low.
On the basis of available information, the test substance Butylstannonic acid can be considered to be not readily biodegradable in nature.
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