Registration Dossier
Registration Dossier
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EC number: 204-640-3 | CAS number: 123-66-0
Endpoint summary
Administrative data
Key value for chemical safety assessment
Genetic toxicity in vitro
Description of key information
All required in vitro tests showed negative results. According to Column 2 in Annex VIII (Section 8.4), an in vivo test is not necessary given the consistently negative results in multiple in vitro studies.
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (negative)
Genetic toxicity in vivo
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
Information are available from reliable study for all the required in vitro endpoints. The results of all studies were in agreement.
In vitro key studies indicate that the test substance is negative in the gene mutation (bacterial reverse mutation assay / Ames test and in mammalian cell gene mutation test / HPRT), with and without metabolic activation and in the in vitro mammalian micronucleus.
Justification for classification or non-classification
Based on the available data, the test substance does not require classification for mutagenicity according to Regulation (EC) No 1272/2008.
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