Registration Dossier
Registration Dossier
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 206-746-5 | CAS number: 372-18-9
Acute Toxicity: inhalation
Administrative data
- Endpoint:
- acute toxicity: inhalation
- Type of information:
- not specified
- Adequacy of study:
- other information
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- abstract
- Remarks:
- Publication in Russian
Data source
Reference
- Reference Type:
- publication
- Title:
- 1,3-DFB: No information
- Author:
- No information
- Year:
- 1 965
- Bibliographic source:
- Izvestiya Sibirskogo Otdeleniya Akademii Nauk SSSR, Seriya Biologomeditsinskikh Nauk. Vol. 3, Pg. 91
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- GLP compliance:
- no
Test material
- Reference substance name:
- 1,3-difluorobenzene
- EC Number:
- 206-746-5
- EC Name:
- 1,3-difluorobenzene
- Cas Number:
- 372-18-9
- Molecular formula:
- C6H4F2
- IUPAC Name:
- 1,3-difluorobenzene
- Test material form:
- liquid
- Details on test material:
- Name of the test material: 1,3-difluorobenzene
No data available
Constituent 1
Test animals
- Species:
- mouse
Administration / exposure
- Route of administration:
- inhalation
- Duration of exposure:
- 2 h
Results and discussion
Effect levelsopen allclose all
- Dose descriptor:
- LC50
- Effect level:
- 55 mg/L air
- Exp. duration:
- 2 h
- Dose descriptor:
- LC50
- Effect level:
- 43.65 mg/L air
- Exp. duration:
- 4 h
- Remarks on result:
- other: calculated with Haber's law
- Clinical signs:
- other: Brain and coverings: recordings from specific areas of central nervous system
Applicant's summary and conclusion
- Interpretation of results:
- GHS criteria not met
- Conclusions:
- The acute inhalation LC50 - 2h value of 1,3-difluorobenzene was found to be 55 mg/L in mouse. The LC50 - 4h calculated with Haber's law was found to be 43.65 mg/L.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
