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Toxicological information

Eye irritation

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Administrative data

Endpoint:
eye irritation: in vivo
Type of information:
experimental study
Adequacy of study:
weight of evidence
Study period:
1976
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Remarks:
Only results given (methodical details are missing)

Data source

Reference
Reference Type:
publication
Title:
Unnamed
Year:
1984
Report date:
1984

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: Toxicity test for bulk chemicals to meet DOT regulations (April 24, 1973)
GLP compliance:
no
Remarks:
Data from 1976 (at this time GLP was not compulsory)

Test material

Constituent 1
Chemical structure
Reference substance name:
Benzophenone
EC Number:
204-337-6
EC Name:
Benzophenone
Cas Number:
119-61-9
Molecular formula:
C13H10O
IUPAC Name:
benzophenone
Details on test material:
not further specified

Test animals / tissue source

Species:
rabbit
Strain:
not specified
Details on test animals or tissues and environmental conditions:
not further specified

Test system

Vehicle:
not specified
Controls:
not specified
Amount / concentration applied:
not further specified
Duration of treatment / exposure:
not further specified
Observation period (in vivo):
not further specified
Number of animals or in vitro replicates:
not further specified
Details on study design:
not further specified

Results and discussion

In vivo

Results
Irritation parameter:
other: The treatment caused no eye irritation.
Remarks on result:
no indication of irritation
Irritant / corrosive response data:
The treatment caused no eye irritation.

Any other information on results incl. tables

The treatment caused no eye irritation.

Applicant's summary and conclusion

Interpretation of results:
GHS criteria not met
Conclusions:
The treatment caused no eye irritation.
Executive summary:

In this study with rabbits the application of benzophenone caused no eye irritation. Thus benzophenone is not subject of classification.