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Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

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Reference
Endpoint:
toxicity to aquatic algae and cyanobacteria
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2008
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study without detailed documentation
Qualifier:
according to guideline
Guideline:
OECD Guideline 201 (Alga, Growth Inhibition Test)
Deviations:
no
GLP compliance:
yes
Analytical monitoring:
yes
Remarks:
No further details.
Details on sampling:
The concentration of the test substance in the test solution was measured at the beginning and the end of exposure, and the average value was between 95% and 100% of the set concentration.
Vehicle:
not specified
Test organisms (species):
Pseudokirchneriella subcapitata (previous names: Raphidocelis subcapitata, Selenastrum capricornutum)
Test type:
not specified
Water media type:
freshwater
Limit test:
no
Total exposure duration:
72 h
Nominal and measured concentrations:
Not specified.
Reference substance (positive control):
not specified
Key result
Duration:
72 h
Dose descriptor:
EC50
Effect conc.:
12 mg/L
Nominal / measured:
not specified
Conc. based on:
test mat.
Basis for effect:
growth rate
Key result
Duration:
72 h
Dose descriptor:
NOEC
Effect conc.:
2.1 mg/L
Nominal / measured:
not specified
Conc. based on:
test mat.
Basis for effect:
growth rate
Validity criteria fulfilled:
not specified
Conclusions:
Based on the growth rate, the 72h-EC50 of the test item in algae is 12 mg/L and the 72h-NOEC is 2.1 mg/L.
Executive summary:

A growth inhibition test was conducted with the test item in Psedokirchneriella subcapitata, according to the OECD guideline 201, under GLP conditions. The test item concentration was measured at the beginning and at the end of the exposure time, and remained within 95 -100% of the nominal value. Based on the growth rate, the 72h-EC50 of the test item in algae was found to be 12 mg/L and the 72h-NOEC was 2.1 mg/L (average value of the measured concentration).

Description of key information

Key study. Method according to OECD 201, GLP study. The 72h-EC50 of the test item in algae is 12 mg/L, and the 72h-NOEC is 2.1 mg/L.

Key value for chemical safety assessment

EC50 for freshwater algae:
12 mg/L
EC10 or NOEC for freshwater algae:
2.1 mg/L

Additional information

A growth inhibition test was conducted with the test item inPsedokirchneriella subcapitata, according to the OECD guideline 201, under GLP conditions. The test item concentration was measured at the beginning and at the end of the exposure time, and remained within 95 -100% of the nominal value. Based on the growth rate, the 72h-EC50 of the test item in algae was found to be 12 mg/L and the 72h-NOEC was 2.1 mg/L (average value of the measured concentration).