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Environmental fate & pathways

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Additional information

Overview on measured bioaccumulation data in fish

The number of key publications that deserve reliability of 2 is limited: these include those of Japan CITI 1992/NITE 2002, Spacie et al. 1983, and to a certain degree those of de Voogt et al. 1991. The distribution of radiolabelled anthracene was investigated in one well-done lab-scale microcosm study that included several species and compartments (Lu et al 1978).

Reliable experimental BCF values based on valid studies with anthracene in fish range from about 1000 to about 2500.

This is largely consistent with the predicted BCF values obtained from the octanol-water partition coefficient. 

Based on accepted calculations of the BCF (see EC TGD 2003, part 2, p. 126: lgBCF = 0.85*lgKow – 0.70, according to Veith et al. 1979) [also recommended in Guidance CSA (May 2008), Chapter R7C, Tab. R.7.10-3], the predicted BCF would be ~1900. Using the other published and commonly used lgKow of 4.54 (Karickhoff et al. 1979; WHO-EHC 202 1998), then a predicted BCF of 1440 results.

The Guidance CSA (May 2008), Chapter R7C, Tab. R.7.10-4 relates the logKow range from 4.5 to <5 with a BCF range in fish from 2000 to 5000. It is obvious that the BCF values of anthracene based on the logKow values are expected at the low end of this range, indicating B.

Species

BCF

Test system

Type

Val.

References

Fish

Cyprinus carpio

1660-2820

OECD 305 (15 µg/L)

Equi (parent)

2

CITI 1992

Cyprinus carpio

903-2710

OECD 305 (1.5 µg/L)

Equi (parent)

2

CITI 1992

Gambusia affinis

1029

lab-scale microcosm

Equi (parent),

2

Lu et al. 1978

L. macrochirus

900

S

k1/k2(total)

2

Spacie et al. 1983

L. macrochirus

675

S

k1/k2(corrected)

2?

Spacie et al. 1983

P. reticulata

3900

S

Equi (parent)

2

De Voogt et al. 1991a

P. reticulata

7260

S

k1/k2(parent)

3

De Voogt et al. 1991b

P. reticulata

4550

R

Equi (parent)

3

De Voogt et al. 1991c

P. promelas

6760

S

k1/k2(parent)

3

De Maagd et al., 1996

Carassius auratus

162

S, initial conc. >> water solubility

 k1/k2(parent)

3

Ogata et al. 1984

L. melanotus

910

S

k1/k2(unclear)

3

Freitag et al. 1985

S = static; R = renewal of test medium; equi = equilibrium method (steady state);  

k1/k2 = kinetic method by determining uptake rate (k1) and elimination rate (k2)