Registration Dossier
Registration Dossier
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EC number: 204-171-4 | CAS number: 117-08-8
Endpoint summary
Administrative data
Key value for chemical safety assessment
Genetic toxicity in vitro
Description of key information
A valid Ames test and a chromosome aberration test (CA) in combination
with a sister chromatid exchange test (SCE) are available for
tetrachlorophthalic anhydride.
Additional a valid HPRT test with phthalic anhydride (as a surrogate for
tetrachlorophthatlic anhydride) is available.
Genetic toxicity in vivo
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (negative)
Additional information
The Ames test and the combined CA and SCE test were negative.
Justification for classification or non-classification
Due to the negative results of the available assays tetrachlorophthalic anhydride is regarded as non-mutagenic. A classification is therefore not justified.
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