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Physical & Chemical properties

Solubility in organic solvents / fat solubility

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Reference
Endpoint:
solubility in organic solvents / fat solubility
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
other: CIPAC MT 157 and CIPAC MT 181
GLP compliance:
yes (incl. QA statement)
Remarks:
Ministerium fur Umwelt, Raumordnung und Landwirtschaft des Landes Nordehein-Westfalen, Dusseldorf.
Medium:
other: n-heptane
Solubility:
50.3 g/L
Temp.:
20 °C
Medium:
acetone
Solubility:
> 250 g/L
Temp.:
20 °C
Medium:
other: 1,2-dichloroethane
Solubility:
> 250 g/L
Temp.:
20 °C
Medium:
ethyl acetate
Solubility:
> 250 g/L
Temp.:
20 °C
Medium:
methanol
Solubility:
> 250 g/L
Temp.:
20 °C
Medium:
other: p-xylene
Solubility:
> 250 g/L
Temp.:
20 °C

Description of key information

Solubility in organic solvents:
 
n-heptane:   50.3 g/L at 20 °C 
Acetone:   > 250 g/L at 20 °C
1,2-dichloroethane:   > 250 g/L at 20 °C
Ethyl acetate:   > 250 g/L at 20 °C
Methanol:   > 250 g/L at 20 °C
p-xylene:   > 250 g/L at 20 °C

Key value for chemical safety assessment

Additional information

A solubility of 50.3 g/L was measured in n-heptane and a solubility of > 250 g/L was measured in each of the following organic solvents; acetone, 1,2-dichloroethane, ethyl acetate, methanol and p-xylene during tests according to CIPAC MT 157 and CIPAC MT 181.